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A Nanoscopic Second Look Into the Knee Joint

This study is looking at how well different knee surgeries heal over time. If you've had or are planning to have knee surgery like meniscus repair or cartilage procedures, you might be able to join. Doctors will use a very small camera, called a nanoscope, to look inside your knee after surgery to see how it has healed. This "second look" will be compared to your pain and function scores, and images from your original surgery. The goal is to see if this nanoscopic view provides helpful information for your recovery and future care. The study is currently recruiting about 15 participants.

Study design
This is an interventional study with a planned enrollment of 15 participants. It involves a single-arm design where all participants will undergo the nanoscopic arthroscopy procedure.
What's involved
If you participate, you will have one clinic visit where a nanoscope will be inserted into your knee. You will also fill out surveys about your knee's function and pain.
Compensation
Not stated in the trial record.
Follow-up
Your healing will be assessed from your preoperative assessment up to 3 to 24 months after your initial knee surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07709819

A Nanoscopic Second Look Into the Knee Joint

Recruiting
NAAges 18+InterventionalDiagnostic
Angelina Vera MD
~15 participants
Updated 2026-07-17 on ClinicalTrials.gov
What's tested:Nanoscopic Arthroscopy of the Knee

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Correlation between Estimated Percentage Meniscal Healing at Second Look Nanoscopic Arthroscopy and PROMIS Score.
Measured over From baseline (preoperative assessment) to the postoperative second-look nanoscopic arthroscopy visit (3 to 24 months after the index meniscal repair procedure).

Conditions

Meniscal Tears

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Cartilage DamageLigament InjuryMeniscal Tears

Where it's being run

1 sites across 1 states
Nevada1

Study leadership

  • Angelina Vera, MD, FAAOS, FAANA · PRINCIPAL_INVESTIGATOR · University Medical Center of Southern Nevada

Who to contact

Robert J Panganiban
[email protected]
(702) 383-7336
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults aged 18 years and older who have undergone or are scheduled to undergo arthroscopic knee intervention.
Eligible procedures include meniscus repair, biocartilage procedures, and other arthroscopic biologic interventions of the knee
Ability to understand and provide informed consent
Agreement to undergo postoperative in-clinic second-look nanoscopic arthroscopy of the knee.

Exclusion

Refusal to undergo postoperative in-clinic second-look nanoscopic arthroscopy of the knee.
Inability to provide informed consent.
Individuals who are not yet adults (infants, children, teenagers).
Pregnant women
Prisoners

What this trial measures

  • Correlation between Estimated Percentage Meniscal Healing at Second Look Nanoscopic Arthroscopy and PROMIS Score.From baseline (preoperative assessment) to the postoperative second-look nanoscopic arthroscopy visit (3 to 24 months after the index meniscal repair procedure).

    The primary outcome measure is the correlation between estimated meniscal repair healing and change from baseline in PROMIS Physical Function T-Score. Meniscal healing will be assessed using postoperative second-look nanoscopic arthroscopy images obtained 3 to 24 months after the index procedure. The Principal Investigator or delegated trained investigator will visually estimate healing of the original repair site from 0% to 100%, where 0% indicates no observable healing and 100% indicates complete healing with continuous, stable tissue bridging. PROMIS Physical Function will be assessed using the PROMIS Bank v2.0 Physical Function CAT at baseline and at the postoperative nanoscopic visit. The relationship between estimated healing percentage and PROMIS Physical Function T-Score change will be assessed using Spearman's rank correlation coefficient.