NCT07710989
Mechanisms Evaluating Striatal Systems Imaging: LIFU Effects & Outcomes
Not Yet Recruiting
NAAges 18–64InterventionalTreatmentUniversity of California, San FranciscoInvestigator-initiated
~12 participants
Updated 2026-07-27 on ClinicalTrials.gov
What's tested:LIFU
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Auditory Hallucinations
Measured over Baseline and Post-Treatment (Weekly follow-up for 8 weeks)
+1 more outcome measured
Conditions
Where it's being run
1 sites across 1 statesCalifornia1
Study leadership
- Karuna Subramaniam, PhD · PRINCIPAL_INVESTIGATOR · [email protected]
Who to contact
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What this trial measures
- Auditory HallucinationsBaseline and Post-Treatment (Weekly follow-up for 8 weeks)
We will compare hallucinations after LIFU to caudate with baseline and the sham unfocused sonication condition using the Visual Analog Scale (VAS) and Auditory Vocal Hallucination Rating Scales (AVHRS).
- Caudate-superior temporal cortical (STC) connectivityBaseline and Post-Treatment ( Day 5)
We will compare functional connectivity using Fisher r-to-z values from the CONN toolbox between the caudate and STC after LIFU compared to baseline and the sham unfocused sonication condition