Abstinence Reinforcement Therapy for Veterans Experiencing Homelessness Who Smoke

This study is testing a program called Abstinence Reinforcement Therapy + (ART+) to help Veterans experiencing homelessness stop smoking. ART+ combines counseling (Cognitive Behavioral Therapy for Smoking Cessation), smoking cessation aids like Nicotine Replacement Therapy, Bupropion, or Varenicline, and Mobile Contingency Management. Mobile Contingency Management means you can earn financial prizes for showing you haven't smoked. To join, you must be a Veteran experiencing homelessness, smoke at least 5 cigarettes daily, and be willing to try to quit within 30 days. The study aims to see how many participants successfully quit smoking, confirmed by a breath test, after six months. The current recruitment status is unclear.

Study design
This interventional study plans to enroll 120 participants. It is testing a program that includes behavioral therapy and medications.
What's involved
Not specified in the trial record.
Compensation
Participants can earn financial prizes for showing smoking abstinence through Mobile Contingency Management.
Follow-up
The study will check for prolonged smoking abstinence at a 6-month follow-up after you start.

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NCT07714200

Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness

Not Yet Recruiting
NAAges 18+InterventionalTreatment
VA Office of Research and Development
~120 participants
Updated 2026-07-20 on ClinicalTrials.gov
What's tested:Cognitive Behavioral Therapy for Smoking CessationNicotine Replacement TherapyBupropionVareniclineMobile Contingency ManagementClinic-Based Smoking Cessation Counseling

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants whose self-report of prolonged smoking abstinence is bioverified
Measured over 6-month follow-up, about six months after baseline
Tobacco Use Disorder
1 sites across 1 states
North Carolina1
  • Jean C Beckham, PhD · PRINCIPAL_INVESTIGATOR · Durham VA Medical Center, Durham, NC

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Eligibility criteria

Inclusion

Are homeless
Smoke at least 5 cigarettes daily with CO indicating current smoking at time of screening assessment
Are willing to try to quit smoking in next 30 days

Exclusion

Have uncontrolled psychotic symptoms
Have active substance dependence other than nicotine (participants in partial remission with at least one month sobriety will be included)
Have severely impaired hearing or speech
  • Number of participants whose self-report of prolonged smoking abstinence is bioverified6-month follow-up, about six months after baseline

    Prolonged abstinence is defined as 30 days abstinent. For participants who are not using NRT/vapes/e-cigarettes at follow-up, abstinence will be based upon: 1) self-reported abstinence; 2) no biochemical samples indicating smoking (CO ≥ 5 ppm or cotinine ≥ 6 ng/mL); and 3) at least one sample indicating abstinence (CO \< 5 ppm and/or cotinine \< 6 ng/mL)