NCT07714239
Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure
Not Yet Recruiting
NAAges 18+InterventionalHealth servicesVA Office of Research and DevelopmentGovernment-funded
~585 participants
Updated 2026-07-20 on ClinicalTrials.gov
What's tested:Pharmacist/Cardiologist Virtual Team Digital Consultation
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Guideline-Directed Medical Therapy (GDMT) Optimization Score
Measured over From hospital admission (baseline) to 14 days after discharge (VA direct care) or 14 days after Veteran eligibility identification (VA community care)
Conditions
Where it's being run
1 sites across 1 statesColorado1
Study leadership
- Paul L Hess, MD MS · PRINCIPAL_INVESTIGATOR · Rocky Mountain Regional VA Medical Center, Aurora, CO
Who to contact
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Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Admission to a VA medical center or VA-paid community hospital within the preceding 3 months with a primary diagnosis of heart failure
The primary study cohort will consist of those admitted to a VA medical center, while the secondary study cohort will consist of patients admitted to VA-paid community hospitals
Left ventricular ejection fraction ≤ 40%
Not on optimal guideline-directed heart failure medication classes or doses, as assessed in the electronic health record
Receiving care within one of the 6 participating VA medical centers
Exclusion
Hemodynamic instability
Receiving comfort care measures alone or enrolled in hospice
What this trial measures
- Change in Guideline-Directed Medical Therapy (GDMT) Optimization ScoreFrom hospital admission (baseline) to 14 days after discharge (VA direct care) or 14 days after Veteran eligibility identification (VA community care)
The GDMT Optimization Score reflects the proportion of eligible guideline-recommended heart failure medications prescribed relative to the total for which the Veteran is eligible. Points are assigned as follows - Numerator: ACEI/ARB=1, ARNI=2, evidence-based beta blocker=2, MRA=2, SGLT2i=2, Vericiguat=1, Ivabradine=1, Hydralazine/Nitrates=1. Denominator reflects eligibility for each class. A higher score indicates greater concordance with guidelines.