DRAGON Registry for Liver Cancer and Metastases

The DRAGON Registry is collecting information on patients with liver cancer or liver metastases (cancer that has spread to the liver) that cannot be removed by surgery right away. This registry looks at a procedure called combined portal and hepatic vein embolization (PVE/HVE). This procedure helps the liver grow larger before surgery to remove the tumor. The study aims to understand how well PVE/HVE works and if it is safe. Researchers will also look at how different patient characteristics affect the results. You may be able to join if you are 18 or older and have already had the PVE/HVE procedure or a similar one. The main goals are to see if the tumor can be removed three weeks after the procedure and to track how long patients live over five years. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will collect information from patients. It plans to include about 350 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed from enrollment until five years after the procedure.

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NCT07717437

DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.

Recruiting
Not specifiedAges 18+Observational
Maastricht University Medical Center
~350 participants
Updated 2026-07-21 on ClinicalTrials.gov

At a glance

Recruiting sites
30 of 31 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Resectability three weeks after PVE/HVE and 5 years overall survival
Measured over From enrolment until 5 year follow up
Liver Cancer
Liver Metastases
31 sites across 27 states
State of Vienna2
Ontario2
South Holland2
Barcelona2
Illinois1
Minnesota1
Ohio1
Victoria1
  • Ronald Van Dam, Dr. · PRINCIPAL_INVESTIGATOR · Maastricht Universitair Medisch Centrum

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Eligibility criteria

Inclusion

Patients who have undergone PVE/HVE or technical variations on this procedure
18 Years and older
Men and women
  • Resectability three weeks after PVE/HVE and 5 years overall survivalFrom enrolment until 5 year follow up