Study of a Powered Hip Flexion Device for Multiple Sclerosis

This study is looking at how a powered hip flexion device, the Hypershell X, immediately affects walking ability in people with Multiple Sclerosis (MS). Researchers want to see if using this device can improve how you walk over short distances. You might be able to join if you are 18-80 years old, have relapsing-remitting, primary progressive, or secondary progressive MS, and have weakness in your hip muscles. You also need to be able to walk at least 30 meters without help. The study will measure improvements in your walking speed and how high you lift your foot (foot clearance) while using the device at different power levels. The study plans to enroll 10 participants, but its current status is unclear.

Study design
This interventional study plans to enroll 10 participants. It will test the immediate effects of a powered hip flexion device at different assistance levels.
What's involved
Participants will perform a series of 10-meter walks while wearing the Hypershell X device under various power settings. Motion sensors will be worn during these walks.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints, gait speed and foot clearance, are measured on Day 1, indicating immediate effects of device use.

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NCT07724093

Effects of Powered Hip Flexion Device in Persons With Multiple Sclerosis

Not Yet Recruiting
NAAges 18–80InterventionalTreatment
University of Dayton
~10 participants
Updated 2026-07-23 on ClinicalTrials.gov
What's tested:Powered Hip Flexion Orthosis (Hypershell X)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Gait speed
Measured over Day 1 (immediate effect of device use)
+1 more outcome measured
Multiple Sclerosis (MS) Relapsing Remitting
1 sites across 1 states
Ohio1

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Eligibility criteria

Inclusion

Age 18-80
Diagnosis of relapsing remitting, primary progressive or secondary progressive MS
Unilateral or bilateral hip flexion weakness (Manual muscle testing score of 3 or less)
Ability to walk at least 30 meters without requiring rest and without physical support or assistance from another person.
Waist circumference 26-48", Height 5 '- 6'2", Weight 100-230lbs

Exclusion

Prior regular use of a hip flexion orthosis within the past 6 months.
Cognitive or communication deficits that would limit ability to participate safely.
Significant pain or deformity of the lower extremities that could impact walking ability.
Severe spasticity (Modified Ashworth Score of 3 or 4) of the hips or lower extremities that could impact walking ability.
Any other neurological conditions that may affect gait.
  • Gait speedDay 1 (immediate effect of device use)

    Gait speed measured during a 10 meter walk

  • Foot clearanceDay 1 (immediate effect of device use)

    Distance that the foot clears the ground during the swing phase of gait