Immediate Neuromuscular Responses of the Obliquus Capitis Inferior Following Upper Cervical Manual Therapy

This study is looking at the immediate effects of two types of upper neck (cervical) manual therapy on people with head and neck pain or headaches. Researchers are testing a "Thrust long-axis manipulation of C1-C2" and a "5 second long axis hold traction of C1-C2" to see how they affect the obliquus capitis inferior (OCI) muscle, which is a small muscle in your neck. They will use musculoskeletal ultrasound to measure changes in this muscle before, immediately after, and 24 hours after the treatment. You may be able to join if you are between 18 and 65 years old, can read English, and have no history of neck surgery or serious neck injury. The study aims to enroll 80 participants, but its current recruitment status is unclear.

Study design
This is an interventional study with a prospective, randomized design, meaning participants are randomly assigned to one of the two treatment groups. The study plans to enroll 80 participants.
What's involved
You would receive one of two manual therapy interventions: either a single thrust manipulation or three 5-second long axis hold tractions. Measurements will be taken before the intervention, immediately after, and 24 hours later.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 24 hours after the intervention, with measurements taken at that time.

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NCT07725198

Immediate Neuromuscular Responses of the Obliquus Capitis Inferior Following Upper Cervical Manual Therapy

Recruiting
NAAges 18–65InterventionalTreatment
Florida Gulf Coast University
~80 participants
Updated 2026-07-24 on ClinicalTrials.gov
What's tested:Thrust long-axis manipulation of C1-C2

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
MSK Ultrasound
Measured over before intervention, immediately after, and 24 hours after intervention
Head and Neck
Headache
1 sites across 1 states
Florida1

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Eligibility criteria

Inclusion

read and understand English
no previous history of cervical spine surgery or traumatic cervical injury
no contraindications to cervical manual therapy

Exclusion

any absolute contraindications to cervical manipulation
any other medical condition considered unsafe for manual therapy.
  • MSK Ultrasoundbefore intervention, immediately after, and 24 hours after intervention

    MSK Ultrasound measure of the Obliquues Capitis inferior muscle lenght and width