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Mantram Repetition for Veterans with PTSD and Chronic Pain

This study is looking at two behavioral programs for U.S. Veterans who have both post-traumatic stress disorder (PTSD) and chronic pain. One program is called Mantram Repetition, which is a meditation-based practice. The other is a health education and discussion group. Researchers want to see if Mantram Repetition can help reduce PTSD symptoms and pain interference (how much pain affects your daily life) compared to health education. You might be able to join if you are a U.S. Veteran, have a diagnosis of PTSD, and have chronic pain that has lasted at least 6 months. The study is currently unclear about its recruitment status.

Study design
This study is an interventional study planning to enroll 170 participants. It compares two different behavioral programs.
What's involved
Participants will be measured at 0, 5, 10, and 20 weeks to track changes in PTSD symptoms and pain interference.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 20 weeks after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07725588

Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain

Not Yet Recruiting
NAAges 18+InterventionalTreatment
VA Office of Research and Development
~170 participants
Updated 2026-07-27 on ClinicalTrials.gov
What's tested:Mantram Repetition Program for PTSD + PainHealth Education while Living with Pain

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The Revised Clinician-Administered PTSD scale for DSM-5 (CAPS-5-R)
Measured over 0, 5, 10, 20 weeks
+1 more outcome measured

Conditions

Stress Disorders, Post-Traumatic
Pain, Chronic

Explore related trials

Chronic PainPost-Traumatic Stress Disorder

Where it's being run

1 sites across 1 states
California1

Study leadership

  • Anne L Malaktaris · PRINCIPAL_INVESTIGATOR · VA San Diego Healthcare System, San Diego, CA

Who to contact

Anne L Malaktaris
[email protected]
(858) 642-3794
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

U.S. Veteran
Diagnosis of PTSD
Chronic, non-malignant pain:
(a) pain most days (\> 3 days/week) for at least 6 months
(b) average pain severity and interference with enjoyment of life and/or general
Willing/able to engage in study activities

Exclusion

Significant current risk of suicide or homicide
Untreated severe alcohol or substance use disorder
Untreated/unstable serious mental health disorders, such as psychotic disorders, bipolar disorder, or serious dissociative symptoms
Impaired mental status
Concurrent interventions specifically targeting PTSD or CP or social functioning (e.g., couples therapy) or any meditative or mind-body intervention

What this trial measures

  • The Revised Clinician-Administered PTSD scale for DSM-5 (CAPS-5-R)0, 5, 10, 20 weeks

    The CAPS-5-R is a widely-used, well-validated clinician interview that diagnoses PTSD and assesses the severity of PTSD symptoms. Total severity scores range from 0-200, with higher scores indicated greater severity.

  • Patient Reported Outcome Short Form Pain Interference (PROMIS-PI short form v1.1)0, 5, 10, 20 weeks

    The PROMIS-PI short form is a self-report measure of pain-related functional interference. PROMIS-PI items are self-rated from 1 to 5; responses range from 1 ("not at all") to 5 ("very much"). The PROMIS-PI is psychometrically sound and provides meaningful estimates of change in pain interference in clinical samples.