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Hard Gum Chewing and Facial Shape Study

This study is looking at whether chewing a special hard gum, called Jawliner®, can change the shape of your face. Researchers want to see if chewing this gum every other day for four weeks makes a measurable difference in healthy adults. They will use 3D pictures of your face to see these changes. To join, you need to be a healthy adult between 20 and 40 years old, a non-smoker, and have most of your natural teeth. The study is currently unclear on its recruitment status. The main goal is to see how your facial shape changes after chewing the gum, and then again after a break.

Study design
This is an interventional pilot study involving 20 healthy adults. It is not specified if it's randomized or blinded.
What's involved
You would chew Jawliner® hard gum every other day for 4 weeks, with each session lasting about 16 minutes. You will also have three 3D facial imaging appointments over about 8-9 weeks.
Compensation
Not stated in the trial record.
Follow-up
Your facial changes will be measured at baseline, after 4-5 weeks, and again after 8-9 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07726511

Effects of Hard Gum Chewing on Facial Soft Tissue Morphology

Recruiting
NAAges 20–40InterventionalBasic science
UConn Health
~20 participants
Updated 2026-07-24 on ClinicalTrials.gov
What's tested:Hard Gum Chewing

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Changes in Facial Morphology Assessed by 3dMD Stereophotogrammetry
Measured over Baseline (T0), Post-Intervention (T1, 4-5 weeks), and Washout (T2, 8-9 weeks)

Conditions

Face

Explore related trials

Facial Soft Tissue Morphology

Where it's being run

1 sites across 1 states
Connecticut1

Study leadership

  • Flavio Uribe · PRINCIPAL_INVESTIGATOR · UConn School of dental medicine
  • Thais Fernandes Poleti, PhD · PRINCIPAL_INVESTIGATOR · UConn School of dental medicine

Who to contact

Flavio Uribe (Chair, Depto Orthodontics; UConn School of dental medic
[email protected]
860-679-3170
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Healthy, non-smoking adults.
Age 20 to 40 years.
Presence of a full dentition from central incisor to first molar in all four quadrants, excluding second molars.
Stable occlusion with no ongoing orthodontic treatment or myofunctional therapy.
Ability and willingness to comply with the prescribed hard-gum chewing regimen for 4 weeks and attend all study visits.
Ability to provide written informed consent.

Exclusion

Age younger than 20 years or older than 40 years.
Evident facial asymmetry from a frontal view.
Signs or symptoms of temporomandibular disorders (TMD) according to the Diagnostic Criteria for TMD (DC/TMD).
Less than the normal range of condylar motion during maximum opening and closing.
Parafunctional habits such as bruxism with pain, clenching, or habitual gum chewing for more than 1 hour per day.
History of major craniofacial trauma, orthognathic surgery, or congenital craniofacial anomalies.
Ongoing orthodontic treatment or recent removal of fixed appliances (\<6 months).
Significant malocclusion or missing teeth in the anterior or premolar-first molar region that may affect mastication.
Systemic diseases or medications affecting muscle or bone metabolism.
Previous use of botulinum toxin (Botox) within the last 6 months or anticipated use during the study period.
Pregnancy or lactation.
Allergy or intolerance to the chewing gum ingredients.

What this trial measures

  • Changes in Facial Morphology Assessed by 3dMD StereophotogrammetryBaseline (T0), Post-Intervention (T1, 4-5 weeks), and Washout (T2, 8-9 weeks)

    Quantification of facial morphology changes using three-dimensional stereophotogrammetry, including regional surface distance maps (heatmaps), linear and angular measurements, and global and regional RMS deviation values.