PCOS and Brain Health Study
This study is looking at how Polycystic Ovary Syndrome (PCOS) affects brain health. Researchers want to understand if PCOS changes how blood flows in the brain (Cerebral Blood Flow or CBF), the brain's structure, and how well people perform on thinking tasks. They will enroll 45 women, both with and without PCOS, between the ages of 18 and 45. You would have two visits, including an MRI scan of your brain and other tests. The study aims to see if women with PCOS have reduced CBF or changes in brain structure and thinking abilities compared to women without PCOS. The study's current status is unclear.
- Study design
- This is an observational study with a planned enrollment of 45 participants. It is not specified if the study is randomized or blinded.
- What's involved
- You would have two visits, including a 1.5-hour MRI scan (55-60 minutes in the MRI) and a laboratory visit for a DEXA scan, cognitive tests, and an optional exercise test. Your participation would last approximately 5 hours over a 1 to 3 month period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Primary endpoints, like Cerebral Blood Flow and Circulating Sex Hormone Levels, will be measured at data collected during a 2-hour MRI visit (anytime up to 3 months on study).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
PCOS and Brain Health
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Laura Cooney, MD · PRINCIPAL_INVESTIGATOR · University of Wisconsin, Madison
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Cerebral Blood Flow (CBF) at restdata collected during a 2-hour MRI visit (anytime up to 3 months on study)
Arterial Spin Labeling (ASL) color atlases and 4D Flow MRI will be used to measure CBF at rest. CBF will be measured in each of six brain regions: temporal, parietal, frontal, occipital, subcortical, and brainstem.
- Circulating Sex Hormone Levelsdata collected during a 2-hour MRI visit (anytime up to 3 months on study)