Screen2Prevent (S2P) HIV Screening Study
This study, called Screen2Prevent (S2P), is looking at different ways to screen young people for HIV in emergency departments (EDs). It aims to find the best approach to identify HIV infections and quickly connect patients to HIV Pre-Exposure Prophylaxis (PrEP), a medicine to prevent HIV, or Antiretroviral Treatment (ART), medicines to treat HIV. The study will test three different screening strategies: targeted screening (for those at higher risk), universally offered opt-in screening (where everyone is offered a test and can choose to take it), and universally offered opt-out screening (where everyone is offered a test unless they say no). Researchers will measure how many new HIV cases are found each month and how quickly PrEP/ART is started after an ED visit. You can join if you are between 14 and 24 years old and visit a participating ED.
- Study design
- This interventional study will test three different HIV screening strategies, each for 8 months, over a total of 24 months. It plans to enroll 84,000 participants.
- What's involved
- You would be offered a computerized sexual health survey on a tablet during your ED visit. You can choose whether or not to complete the survey.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study will measure outcomes related to HIV detection and PrEP/ART initiation at 36 months.
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Screen2Prevent (S2P)
At a glance
Conditions
Where it's being run
5 sites across 5 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
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What this trial measures
- Monthly HIV detection rates per 1,000 eligible patients36 months
Compare the rate of HIV detection between each screening strategy (targeted, universal opt-in, universal opt-out) to baseline using the all patients analysis set.
- Rapid PrEP/ART initiation (defined by prescription within 72 hours of ED discharge)36 months
Compare the rates of rapid start of PrEP/ART, defined as PrEP/ART prescription within 72 hours of ED discharge, between adolescents and young adults who visit the ED prior to implementation of cSHS and those who visit after implementation of cSHS using the all patients analysis set.