Diet, Metabolic Health, and Exercise Responses Study

This observational study is looking at how your diet, specifically fat quality, and your metabolic health (how your body uses energy) might be connected to your responses to exercise and your brain function. Researchers want to understand why people react differently to exercise. You might be able to join if you are between 18 and 60 years old, can complete two lab visits, and are able to safely do moderate-intensity cycling. The study will measure your feelings during and after a 30-minute cycling session, as well as your perceived arousal (how alert or stimulated you feel) and positive emotions. The current status of this study is unclear, and it plans to enroll 100 participants.

Study design
This is an observational study, meaning researchers will observe and collect information without giving you a specific treatment. It plans to include 100 participants.
What's involved
You would complete two laboratory visits, record your diet, undergo cognitive assessments, and participate in exercise testing, including a 30-minute moderate-intensity cycling session.
Compensation
Not stated in the trial record.
Follow-up
Your affective valence, perceived arousal, and positive affect will be measured immediately before, during, immediately after, and 30 minutes after the 30-minute cycling session.

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NCT07728240

Diet, Metabolic Health, and Exercise Responses

Recruiting
Not specifiedAges 18–60Observational
University of Wisconsin, River Falls
~100 participants
Updated 2026-07-27 on ClinicalTrials.gov
What's tested:Standardized Moderate-Intensity Cycling Session

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Affective Valence During and After Exercise
Measured over Immediately before exercise; at minutes 5, 10, 15, 20, and 25 during the 30-minute cycling session; immediately after exercise; and 30 minutes after exercise
+3 more outcomes measured
Diet Quality
Metabolic Health
Cognitive Function
Exercise Response
1 sites across 1 states
Wisconsin1
  • Gregory Ruegsegger, PhD · PRINCIPAL_INVESTIGATOR · University of Wisconsin, River Falls

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Eligibility criteria

Inclusion

Age 18 years or older.
Able to provide written informed consent.
Able and willing to complete two laboratory visits, dietary recording, cognitive assessments, and exercise testing.
Able to safely complete submaximal exercise testing and a 30-minute moderate-intensity cycling session, as determined by health-history screening and the Physical Activity Readiness Questionnaire Plus (PAR-Q+).
Willing to complete dietary records and follow pre-visit instructions.

Exclusion

Known cardiovascular, pulmonary, metabolic, neurological, psychiatric, or other medical condition that could make exercise testing or moderate-intensity exercise unsafe or substantially affect study outcomes.
Current pregnancy.
Current smoking.
Medication use that could substantially affect metabolic, cardiovascular, cognitive, or exercise-response outcomes, as determined by the investigators.
Resting heart rate greater than 100 beats per minute.
Resting blood pressure greater than 160/100 mmHg.
Electrocardiogram abnormality requiring further medical evaluation.
Positive PAR-Q+ response or other health-screening finding indicating that medical clearance is required and has not been obtained.
Inability or unwillingness to complete study procedures, fasting requirements, dietary records, or pre-visit restrictions.
Any other condition that, in the judgment of the research team, would make participation unsafe or interfere with valid completion of the study procedures.
  • Affective Valence During and After ExerciseImmediately before exercise; at minutes 5, 10, 15, 20, and 25 during the 30-minute cycling session; immediately after exercise; and 30 minutes after exercise

    Affective valence will be assessed using the single-item Feeling Scale. Scores range from -5 ("very bad") to +5 ("very good"), with 0 representing "neutral." Higher scores indicate more positive affective valence and therefore a better affective response.

  • Perceived Arousal During and After ExerciseImmediately before exercise; at minutes 5, 10, 15, 20, and 25 during the 30-minute cycling session; immediately after exercise; and 30 minutes after exercise

    Perceived arousal will be assessed using the single-item Felt Arousal Scale. Scores range from 1 ("low arousal") to 6 ("high arousal"). Higher scores indicate greater perceived arousal and are not inherently a better or worse outcome.

  • Positive Affect Before and After ExerciseImmediately before exercise, immediately after the 30-minute cycling session, and 30 minutes after exercise

    Positive affect will be assessed using the five-item positive-affect subscale of the International Positive and Negative Affect Schedule-Short Form. The five items are summed to produce a score ranging from 5 to 25. Higher scores indicate greater positive affect and therefore a better affective response.

  • Negative Affect Before and After ExerciseImmediately before exercise, immediately after the 30-minute cycling session, and 30 minutes after exercise

    Negative affect will be assessed using the five-item negative-affect subscale of the International Positive and Negative Affect Schedule-Short Form. The five items are summed to produce a score ranging from 5 to 25. Higher scores indicate greater negative affect and therefore a worse affective response.