This study is testing a new treatment called EO2002 for people with corneal edema (swelling of the clear front part of your eye) caused by problems with the corneal endothelium (the inner layer of cells in your cornea). This condition can be due to Fuchs dystrophy or other causes. Researchers want to see if a single injection of EO2002, at one of two different doses, can improve your vision and is safe, compared to a placebo (an inactive injection). You may be able to join if you have symptomatic central corneal edema affecting your vision, and your vision is within a specific range. The study aims to enroll about 121 participants.

Study design

This study is an interventional trial that will randomly assign participants to receive one of two doses of EO2002 or a placebo. Approximately 121 participants are planned to be enrolled.

What's involved

Participants will receive a single injection and will be followed for 52 weeks to evaluate safety and efficacy.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for 52 weeks after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.