A Study of PF-08642534 for Obesity

This study is looking at a medicine called PF-08642534 for people who have obesity (too much body weight). Researchers want to find out if different amounts of PF-08642534 are safe and how well people tolerate them. They also want to understand how the body uses and removes the medicine. You might be able to join if you are between 18 and 70 years old, have a Body Mass Index (BMI) between 30.0 and 40.0 kg/m², and are generally healthy. People with certain medical conditions, like diabetes or significant heart problems, cannot participate. The main goal is to track any side effects you might experience up to 8 weeks after your last dose.

Study design
This is an interventional study planning to enroll 120 participants. Some participants will receive PF-08642534 once a day, while others will receive a placebo (an inactive substance) once a day.
What's involved
You will go through a screening period of up to 4 weeks to see if you meet the study requirements.
Compensation
Not stated in the trial record.
Follow-up
You will be monitored for side effects up to 8 weeks after your last dose of the study medicine.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07731139

A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity

Not Yet Recruiting
PHASE1Ages 18–70InterventionalBasic science
Pfizer
~120 participants
Updated 2026-07-28 on ClinicalTrials.gov
What's tested:PF-08642534Placebo

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of treatment emergent adverse events (TEAE)
Measured over Baseline up to 8 weeks after last dose
Obesity
1 sites across 1 states
California1
  • Pfizer CT.gov Call Center · STUDY_DIRECTOR · Pfizer

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  • Incidence of treatment emergent adverse events (TEAE)Baseline up to 8 weeks after last dose