Cryoneurolysis for Pain After ACL Reconstruction
This study is looking at whether a treatment called cryoneurolysis (using cold to block nerves) can help reduce pain and the need for opioid medications after anterior cruciate ligament (ACL) reconstruction surgery. You might be eligible if you are between 18 and 45 years old, are having your first ACL reconstruction with a specific type of graft (bone-patellar tendon-bone autograft), and haven't used opioids long-term before surgery. The study will compare the Pacira Iovera Cryoneurolysis device to a sham device that looks the same but doesn't provide treatment. Researchers will measure your knee function and recovery one month after surgery to see if the cryoneurolysis treatment is helpful. The current status of this study is unclear.
- Study design
- This is an interventional study planning to enroll 150 participants. It compares the Pacira Iovera Cryoneurolysis device to a placebo/sham device.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for at least one month after surgery to assess knee function.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Cryoneurolysis in Anterior Cruciate Ligament Reconstruction (ACLR)
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Eric J. Strauss, MD · PRINCIPAL_INVESTIGATOR · NYU Langone Health
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Difference in Knee Injury and Osteoarthritis Outcome Score (KOOS)Baseline, 1 Month
The KOOS survey is comprised of 42 questions. The questions are divided into 5 sub-categories: symptoms (7 questions), pain (9 questions), function/daily living (17 questions), function/sports and recreational activities (5 questions), and quality of life (4 questions). The total range for each sub-category is 0-100, making the total range for the whole survey 0-500. The higher the score, the worse the symptoms and pain/ higher difficulty in function.
- Difference in Lysholm knee scoring scale (LKSS)Baseline, 1 Month
The Lysholm knee scoring scale is a 100-point patient-reported questionnaire designed to assess functional knee ligament injuries. It evaluates eight areas - limp, support, locking, instability, pain, swelling, stair climbing, and squatting - with higher scores (up to 100) indicating better function.