Understanding Cancer Drug Benefits: A Study for Patients

This study aims to understand how different explanations of cancer drug benefits affect patients' expectations. It's looking at how people with a current or past cancer diagnosis (excluding nonmelanoma skin cancer) understand "progression-free survival" (PFS), which is the time a patient lives with cancer without it getting worse. You'll be presented with different ways of explaining PFS, including those from the FDA and National Cancer Institute, and a plain-language version. Some explanations will also include information about "overall survival" (how long a person lives). The study wants to see if adding overall survival data helps patients better understand the true benefits of new cancer drugs. The goal is to improve how information is shared so patients can make informed decisions. This study is for US adults, 18 or older, who speak English and have had cancer.

Study design
This is an interventional study planning to enroll 3000 participants. It will compare different ways of explaining cancer drug benefits.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your expectations about survival benefits will be assessed immediately after you receive the information.

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NCT07731425

Patients' Expectations About the Survival Benefits of Cancer Drugs Approved Based on Progression-Free Survival

Not Yet Recruiting
NAAges 18+Interventional
London School of Economics and Political Science
~3,000 participants
Updated 2026-07-28 on ClinicalTrials.gov
What's tested:FDA explanation for progression-free survival (control)FDA explanation for progression-free survival with overall survival dataNCI explanation for progression-free survivalNCI explanation for progression-free survival with overall survival dataPlain-language explanation of progression-free survivalPlain-language explanation of progression-free survival with overall survival data

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Accuracy of expectations about the survival benefits of a new cancer drug approved based on progression-free survival
Measured over Assessed immediately after the intervention
Cancer
1 sites across 1 states
Massachusetts1

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Eligibility criteria

Inclusion

US adults with a current or former cancer diagnosis (excluding nonmelanoma skin cancer)
US adults 18 years of age and older, fluent in English, and residing in the United States.
  • Accuracy of expectations about the survival benefits of a new cancer drug approved based on progression-free survivalAssessed immediately after the intervention

    Compared to standard treatment, do patients with advanced kidney cancer live longer when treated with Velotrex? \- Response options: definitely yes, probably yes, probably no, definitely no