Home-Based Walking for Thinking Skills in Persons With TBI

This study is looking at whether a 3-month home-based walking program can help improve thinking skills in people who have had a traumatic brain injury (TBI). You can join if you are 18-65 years old, have a TBI diagnosis from at least one year ago, and experience problems with thinking skills like remembering or organizing. You also need internet access and to be able to walk at a brisk pace without help. The study aims to see if participants stick to the walking program and if there are any side effects. You will either start the walking program right away or after a 3-month waiting period. The study is currently unclear on its recruitment status and plans to enroll 40 participants.

Study design
This is an interventional study with 40 planned participants. You will be randomly assigned to one of two groups, like flipping a coin, with a 50/50 chance of being in either group.
What's involved
You will complete an initial 1-hour video call for thinking tests and questionnaires. If in the walking group, you will walk 3 times per week for 3 months, starting with 10 minutes and increasing over time. You will have regular video meetings with a trainer.
Compensation
Not stated in the trial record.
Follow-up
Participants in the intervention group will be followed for 3 months, and those in the wait-list group for 6 months.

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NCT07733284

Home-Based Walking for Thinking Skills in Persons With TBI

Recruiting
EARLY_PHASE1Ages 18–65InterventionalTreatment
Kessler Foundation
~40 participants
Updated 2026-07-29 on ClinicalTrials.gov
What's tested:Walking

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Adverse Events
Measured over Through study completion, which is 3 months for intervention and 6 months for wait list.
+2 more outcomes measured
Traumatic Brain Injury (TBI) Patients
1 sites across 1 states
New Jersey1

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Eligibility criteria

Inclusion

Definitive TBI diagnosis at least 1 year prior, verified by medical records
Self-report problems with thinking skills since the TBI diagnosis (e.g., processing information, learning or remembering, organizing, multitasking)
Between the ages of 18 and 65
Access to internet and email
Fluent in English
Can walk at a brisk pace without using an assistive device
Not fallen due to mobility issues from their TBI in the past 6 months
Do not currently meet public health guidelines for physical activity
Have problems with thinking performance

Exclusion

I currently have uncontrolled major depression
I have a history of schizophrenia, bipolar disorder I or II, or substance-abuse disorders
I am regularly taking medications that can affect my thinking, such as antipsychotics or benzodiazepines. Study staff will review my medications to determine if I am taking any that would make me ineligible for this study
I have known/diagnosed cardiovascular disease including uncontrolled hypertension, diabetes, or kidney disease
I am unable to make everyday decisions on my own
  • Adverse EventsThrough study completion, which is 3 months for intervention and 6 months for wait list.

    Safety will be primarily measured as adverse events, specifically during the remote walking intervention.

  • AdherenceThrough study completion, which is 3 months for intervention and 6 months for wait list.

    Adherence is measured as the number of exercise sessions attended compared to the number of total sessions prescribed.

  • ComplianceThrough study completion, which is 3 months for intervention and 6 months for wait list.

    Compliance will be measured as the number of exercise sessions completed as prescribed (i.e., intensity and duration).