Geriatric Assessment for Older Adults with Acute Myeloid Leukemia

This study is for adults aged 60 and older who have been newly diagnosed with Acute Myeloid Leukemia (AML), a type of blood cancer. It's testing if using a "geriatric assessment" (GA) to guide treatment choices can reduce side effects and improve how you feel, compared to standard care. The GA helps doctors understand your overall health, not just your age. Depending on your GA results (fit, vulnerable, or frail), you would receive specific treatment regimens. The main goal is to see how many people experience treatment failure within 3 months. This study is currently unclear on its recruitment status.

Study design
This is a Phase 2 randomized controlled trial involving 120 participants. It compares a geriatric assessment-guided treatment strategy to usual oncologist-directed care.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at 3 months after treatment initiation to assess treatment failure rate.

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NCT07735208

Geriatric Assessment-Guided Treatment Selection in Older Adults With Acute Myeloid Leukemia

Not Yet Recruiting
PHASE2Ages 60+InterventionalTreatment
University of Rochester
~120 participants
Updated 2026-07-29 on ClinicalTrials.gov
What's tested:GA-directed treatment regimens

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Treatment failure rate at 3 months
Measured over 3 months after treatment initiation
Acute Myeloid Leukemia
1 sites across 1 states
New York1

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  • Treatment failure rate at 3 months3 months after treatment initiation

    Treatment failure is defined as the occurrence of any of the following within 3 months after treatment initiation: disease progression or relapse, death from any cause, treatment discontinuation for any reason except logistical reasons, absence of at least one agent in the initial treatment regimen for more than 30 days following the last day of the previous treatment cycle (temporary dose interruptions and cycle delays within the 30 day window are not considered treatment failure events), or initiation of an alternative treatment regimen or addition of an agent because of clinician documented concern for lack of efficacy or disease control.