Treatment resistant depression clinical trials
10 active trials name this condition. Describe your situation to see which ones you may be eligible for.
By location
- Mindfulness Engaged Neurostimulation for Depression (MEND II)
- Maintenance rTMS for Depression (Maitr-De)
- Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)
- PCS in Severe Treatment Resistant Depression
- DBS for Depression
- Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression
- A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial
- Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
- Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
- Studying Patterns in Patient Engagement Among Treatment Resistant Depression Patients
Guides for people searching for a trial
- Why people get turned down — and what to do nextWhat eligibility criteria are for, what keeps people out, and where to go when the first door closes.
- How your biomarkers decide which trials you qualify forEGFR, HER2, BRAF, PD-L1 and the rest — what they are and why they increasingly gate access.
- How to search for a trial without losing your mindWhere to look, what to gather first, and how to read what you find.
- What Phase 1, 2 and 3 actually mean for youWhat each phase is testing, and how to weigh an early-phase trial against a later one.
- 10 questions to ask before you say yesTreatment, time, cost, safety and your rights. Worth bringing to a screening visit.
- You matched with a trial. What happens now?Phone screens, the screening visit, informed consent, and day one.
Showing active trials that list “Treatment resistant depression” as a condition. Eligibility shown on each trial is an estimate — the trial's study team makes the final decision.