Evaluation of Mood and Anxiety Disorders and Healthy Volunteers

This study aims to carefully screen patients with mood and anxiety disorders, as well as healthy volunteers, for participation in research studies at the National Institute of Mental Health (NIMH). It also collects information to better understand these conditions. There are no specific interventions (treatments) being tested in this study. Instead, participants will undergo evaluations that may include psychiatric and diagnostic interviews, physical exams, brain scans (MRI, CT, EEG, MEG), and blood, saliva, and urine tests. The main goal is to determine if you are eligible for other research studies. This study is open to individuals aged 3 to 99 years old. The current status of the study is unclear, and it plans to enroll up to 16,000 people.

Study design
This is an observational study, meaning it focuses on collecting information rather than testing a specific treatment. It plans to enroll up to 16,000 participants.
What's involved
You would undergo an evaluation that may include interviews, physical exams, brain imaging (MRI, CT, EEG, MEG), and laboratory tests (blood, saliva, urine).
Compensation
Not stated in the trial record.
Follow-up
Not specified.

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NCT00024635

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

Recruiting
Not specifiedAges 3–99Observational
National Institute of Mental Health (NIMH)
~16,000 participants
Updated 2026-08-11 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Eligibility for research
Measured over Current and historical
Mood Disorders
Anxiety Disorders
Healthy Volunteers
Bipolar Disorder
Depression
1 sites across 1 states
Maryland1
  • Carlos A Zarate, M.D. · PRINCIPAL_INVESTIGATOR · National Institute of Mental Health (NIMH)

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Eligibility criteria

Inclusion

Subjects ages 3 to 99 may enroll in the protocol.
Subjects must be competent to comprehend the purpose of the screening process and to provide written informed consent and be willing to participate in NIMH IRB approved research protocols. Minors will be asked to assent and their parents will sign the consent form.

Exclusion

Current alcohol or substance use or dependence (excluding nicotine) within the past 3 months of sufficient magnitude to require independent, concurrent treatment intervention (e.g. Antabuse or opiate treatment, but not including self-help groups).
  • Eligibility for researchCurrent and historical

    Evaluations of psychiatric and other medical conditions and histories to determine if the subjects are appropriate for participation in NIMH IRB approved protocols and for the collection of natural history data.