Depression clinical trials
357 active trials name this condition. Describe your situation to see which ones look like a fit.
By location
- Clemastine for Improving White Matter and Boosting Antidepressant Response in Late-life Depression
- A Study of Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors
- Assessing Improvements in Mood and Sleep Trial
- WeCare: A System of Care for Black Youth
- The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease
- A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression
- Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)
- Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction
- ICBT (Internet Based Cognitive Behavioral Therapy) for Maternal Depression: Community Implementation in Head Start
- Community-based Approach to Lowering Stress Through Mindfulness
- Promoting Active Therapy: Path to Wellness
- Tele-PROTECT Therapy: Effectiveness, Empowerment, and Implementation
- Physical Capacity Building for Chronic Stroke
- Empower@Home: Community Implementation for Older Adults With Ambulatory Disabilities
- Behavioral Health Program for Short-Stay Nursing Facility Residents & Care Partners
- Telehealth Behavioral Activation for Teens
- Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth
- Brain Stimulation for Severe Depression
- Positive Processes and Transition to Health - Single-Session (PATH-SS)
- Dopaminergic Therapy for Anhedonia - 2
- A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV
- The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study
- Cognitive Behavioral and Faith Fellowship to Improve Thy Health
- Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)
- Neuroscience of Psychotherapy for Depression
- Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)
- Identifying and Treating Depression in the Orthopaedic Trauma Population
- Project HOPEFUL: A PN-RCT With Implementation Science
- Empower@Home: Hybrid Effectiveness-Implementation Randomized Controlled Trial (RCT)
- Mindfulness-Based Interventions Targeting First-Generation College Student Retention in Rural Environments
- The COMParing App Support Strategies Study
- The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
- Training Reward Responsiveness Through Virtual Reality
- S.T.A.N.D. Alacrity Center Signature Project
- Readiness and Progress in Emotion Regulation Therapy
- Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression
- Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With Depression
- Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children
- Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI
- Youth Emotional and Behavioral Treatment Study
- Sleep Promotion Program Primary Care
- Psilocybin-Assisted Therapy for Intergenerational Trauma
- To Improve Depressive Symptoms Using a Web-App
- A Computerized Depression Intervention in Veterans
- Reaching Out to Distressed Medical Residents, Fellows and Faculty
- taVNS or TMS or Both for Depression
- Researching Heat and Yoga for Mood Enhancement
- Better Sleep Study
- Ketamine for Veterans With Parkinson's Disease
- A New Intervention to Improve Function in Veterans With Anxiety and Depression
Guides for people searching for a trial
- Why people get turned down — and what to do nextWhat eligibility criteria are for, what keeps people out, and where to go when the first door closes.
- How your biomarkers decide which trials you qualify forEGFR, HER2, BRAF, PD-L1 and the rest — what they are and why they increasingly gate access.
- How to search for a trial without losing your mindWhere to look, what to gather first, and how to read what you find.
- What Phase 1, 2 and 3 actually mean for youWhat each phase is testing, and how to weigh an early-phase trial against a later one.
- 10 questions to ask before you say yesTreatment, time, cost, safety and your rights. Worth bringing to a screening visit.
- You matched with a trial. What happens now?Phone screens, the screening visit, informed consent, and day one.
Showing active trials that list “Depression” as a condition. Eligibility shown on each trial is an estimate — the trial's study team makes the final decision.