Virtual Reality Training for Depression and Low Positive Affect
This study is exploring if Virtual Reality-Reward Training (VR-RT) can help people with depression and low positive affect (difficulty experiencing positive emotions). VR-RT uses virtual reality experiences and guided memory exercises to help you better enjoy positive moments. We are comparing VR-RT to Virtual Reality-Memory Training (VR-MT), which uses virtual reality and memory exercises for neutral experiences. We want to see if VR-RT can improve your mood and other symptoms more effectively. You may be able to join if you are at least 18 years old, fluent in English, and meet certain scores on questionnaires related to depression and daily functioning. We are looking for 80 participants in total. The study will measure changes in your mood and positive feelings over 12 weeks.
- Study design
- This is an interventional study comparing two virtual reality training methods. 80 participants will be randomly assigned to either Virtual Reality-Reward Training or Virtual Reality-Memory Training.
- What's involved
- Participants will engage in 7 weeks of either Virtual Reality-Reward Training or Virtual Reality-Memory Training. Assessments will occur at the start, mid-treatment, post-treatment, and at a 12-week follow-up.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 12 weeks after the start of the study, with a final assessment at Week 12.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Training Reward Responsiveness Through Virtual Reality
At a glance
Conditions
NCT07219875
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of California, Los Angeles
Los Angeles, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- The Mood and Anxiety Symptoms Questionnaire - Anhedonic Depression Subscale (MASQ-AD)Change from Week 0 assessment to Post-Assessment (Week 8). Change from Week 0 assessment to Follow-Up (Week 12).
Change in reported anhedonia (score range: 14-70), with higher scores indicating greater anhedonic symptom severity
- Positive Valence Systems Scale (PVSS-21)Change from Week 0 assessment to Post-Assessment (Week 8). Change from Week 0 assessment to Follow-Up (Week 12).
Change in reward anticipation, motivation, and consumption for rewards such as rewards such as food, physical touch, positive feedback, social interactions, hobbies and goals (score range: 21-105). Higher scores (e.g. 105) indicate higher reward responsiveness.