Neuroscience of Psychotherapy for Depression Study
This study aims to understand how the brain activity of a client and therapist might synchronize during therapy for depression. It compares two approaches: Behavioral Activation, a type of talk therapy focused on changing behaviors, and Psychoeducation, which provides general information about mental health. You could be eligible if you are between 18 and 30 years old, a full-time student, and have mild to moderate depression symptoms. The study will measure brain activity using EEG (electroencephalography) during a single therapy session and ask you to complete surveys about your mental and physical health. The main goal is to see how brain synchronization in specific frequency bands (Alpha and Theta) changes during the therapy session.
- Study design
- This is a pilot interventional study with a planned enrollment of 45 participants. It compares two behavioral interventions: Psychoeducation and Behavioral Activation.
- What's involved
- You would answer questions about your health, attend one therapy session with simultaneous brain activity measurement, and complete follow-up surveys two weeks and one month later.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will complete follow-up surveys two weeks and one month after the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Neuroscience of Psychotherapy for Depression
At a glance
Conditions
NCT06696001
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Carolina Center for Neurostimulation
Chapel Hill, North Carolinastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Flavio Frohlich · PRINCIPAL_INVESTIGATOR · Carolina Center for Neurostimulation
Who to contact
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Inclusion
Exclusion
What this trial measures
- Inter-brain phase synchronization in Alpha frequency band via Phase Locking ValueDuring the interventional session, approximately 60 minutes
Inter-brain synchronization will be calculated for the Alpha frequency band via phase locking value during the interventional session for both study arms and will be used to assess any potential differences in Alpha frequency inter-brain synchronization between groups
- Inter-brain phase synchronization in Theta frequency band via Phase Locking ValueDuring the interventional session, approximately 60 minutes
Inter-brain synchronization will be calculated for the theta frequency band via phase locking value during the interventional session for both study arms and will be used to assess any potential differences in Theta frequency inter-brain synchronization between groups