Better Sleep Study for Depression in Adolescents

This study, called the Better Sleep Study, is looking at whether improving sleep patterns can help teenagers aged 12 to 18 who have depression and a sleep problem called Delayed Sleep Phase (when your body's internal clock is out of sync with your wake-up time). It's testing two behavioral interventions: TranS-C (Transdiagnostic Sleep and Circadian Intervention), which is a type of sleep therapy, and Psychoeducation, which provides information on how sleep, stress, and mood are connected. The study aims to see if these interventions can improve depression symptoms and better align your biological clock with your wake-up time. The study plans to enroll 200 participants, but its current status is unclear.

Study design
This interventional study plans to enroll 200 participants aged 12 to 18 years old. The phase of the study is not specified.
What's involved
Participants will receive behavioral interventions over approximately 2 months. Assessments will be done at the beginning, end of treatment (2 months), and at 8 and 14 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for changes in depression and sleep patterns at 8 and 14 months after the start of treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06139861

Better Sleep Study

Recruiting
NAAges 12–18InterventionalTreatment
Children's Hospital Los Angeles
~200 participants
Updated 2026-05-11 on ClinicalTrials.gov
What's tested:TranS-CPsychoeducation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in phase angle difference (PAD) between DLMO and waketime (PADDLMO WAKETIME )
Measured over baseline to end of treatment (0 and 2 months)
+1 more outcome measured
Depression in Adolescence
Delayed Sleep Phase

NCT06139861

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Children's Hospital Los Angeles

    Los Angeles, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Lauren M Asarnow, PhD · PRINCIPAL_INVESTIGATOR · Children's Hospital Los Angeles

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Eligibility criteria

Exclusion

mental health/behavioral symptoms that would preclude productive engagement in study assessments or intervention (e.g., active psychosis; Bipolar Disorder; drug dependence
severe or unstable medical or psychiatric condition such that treatment has changed within the last month or is expected to change during the course of the study or that would preclude ability to adhere to study procedures (e.g. terminal end-stage cancer)
current use of medications or herbs with known effects on sleep
plan to undergo or have had medication change in the last 8 weeks
  • Change in phase angle difference (PAD) between DLMO and waketime (PADDLMO WAKETIME )baseline to end of treatment (0 and 2 months)

    Validated biological and behavioral assessment; range between 0 and 11 hours, with shorter numbers indicating worse alignment between circadian biology and behavior

  • Change in Children's Depression Rating Scale (CDRS-R)baseline to end of treatment (anticipated average exposure 2 months), months 8 and 14

    Validated clinician administered depression symptom severity scale; range between 17 and 133, with higher numbers indicative of greater depression severity