PATH-SS for PTSD and Depression after Sexual Assault

This study is testing a new, brief talk therapy called Positive Processes and Transition to Health - Single-Session (PATH-SS). It aims to help people aged 18-65 in Ohio who have experienced a sexual assault within the last 5 years and are struggling with symptoms of PTSD (Post-Traumatic Stress Disorder) or depression. The researchers want to see if PATH-SS can reduce these symptoms and if participants find the therapy helpful. The study plans to enroll 45 participants and is currently unclear on its recruitment status.

Study design
This is an open trial (meaning both participants and researchers know what treatment is being given) for 45 adults. It is an interventional study, meaning participants will receive a specific treatment.
What's involved
You would attend a pre-treatment assessment, one 2-hour PATH-SS therapy session, and then two follow-up assessments, each lasting about 1 hour, over a 1-month period.
Compensation
You will receive a $20 Amazon or Visa gift card for each assessment completed after the treatment session.
Follow-up
Your symptoms will be assessed at 1 month after completing the treatment.

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NCT06900712

Positive Processes and Transition to Health - Single-Session (PATH-SS)

Recruiting
NAAges 18–65InterventionalTreatment
Case Western Reserve University
~45 participants
Updated 2026-04-22 on ClinicalTrials.gov
What's tested:PATH-SS

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
PTSD Symptom Scale-Interview (PSS-I-5; Foa et al., 2016)
Measured over From baseline to follow-up at 1 month after treatment completion
+3 more outcomes measured
PTSD
Depression
1 sites across 1 states
Ohio1
  • Norah C Feeny, PhD · PRINCIPAL_INVESTIGATOR · Case Western Reserve University

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  • PTSD Symptom Scale-Interview (PSS-I-5; Foa et al., 2016)From baseline to follow-up at 1 month after treatment completion

    The PSS-I is a 24-item, state-of-the-art, psychometrically-validated interview used to assess DSM-5 criteria for PTSD and symptom severity. The PSS-I-5 includes 20 questions assessing symptom severity on a 5-point Likert scale (0 = not at all, 4 = six or more times a week/severe), and scores are calculated by summing responses, with higher scores indicating higher PTSD severity, as well as two questions assessing distress and interference and two questions assessing symptom onset and duration.

  • Quick Inventory of Depressive Symptomatology-Clinican Report (QIDS-C; Rush et al., 2003)From baseline to follow-up at 1 month after treatment completion

    The QIDS-C is a 16 item, state-of-the-art, psychometrically-validated interview used to assess depression. Items are rated on a 4-point scale with anchors that vary with the question (e.g., 0 = I do not feel sad, 3 = I feel sad nearly all of the time).

  • Post-traumatic Stress Diagnostic Scale (PDS-5; Foa et al., 2016)From baseline to follow-up at 1 month after treatment completion

    The PDS-5 is a 24-item self-report measure used to assess prior trauma exposure and subsequent PTSD symptoms in the past month. The PDS-5 uses a trauma screen to identify prior exposure to traumatic events and assesses the severity of DSM-5 PTSD symptoms related to the event causing the most distress. The PDS-5 includes 20 questions assessing symptom severity on a 5-point Likert scale (0 = not at all, 4 = six or more times a week/severe), and scores are calculated by summing responses, with higher scores indicating higher PTSD severity. The PDS-5 also includes two questions assessing distress and interference and two questions assessing symptom onset and duration.

  • Quick Inventory of Depressive Symptomatology Self-Report Version (QIDS-SR; Rush et al., 2003)From baseline to follow-up at 1 month after treatment completion

    The QIDS-SR is a 16-item self-report measure that assesses depression. Items are rated on a 4-point scale with anchors that vary with the question (e.g., 0 = I do not feel sad, 3 = I feel sad nearly all of the time).