Identifying and Treating Depression in Orthopaedic Trauma Patients
This study aims to find better ways for orthopaedic surgeons to identify and treat depression in patients who have experienced a bone fracture requiring surgery. Researchers want to see how patients who screen positive for depression respond to either Fluoxetine 20 MG or Duloxetine 30 MG, which are medications commonly used for depression. They will also look at outcomes for patients who choose not to take medication but are referred to behavioral health resources. You might be able to join if you are 18 or older, speak English or Spanish, have recently had an orthopaedic trauma, and score 5 or higher on a depression screening questionnaire (PHQ-9). The study will measure changes in your depression symptoms over 6 months. The current status of this study is unclear, and it plans to enroll 100 participants.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment or intervention. It plans to enroll 100 participants.
- What's involved
- Your depressive symptom scores will be measured at the start of the study, and then again at 3 months and 6 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 6 months after starting the study.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Identifying and Treating Depression in the Orthopaedic Trauma Population
At a glance
Conditions
NCT05976347
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Wake Forest University Health Sciences
Winston-Salem, North Carolinastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Meghan K Wally, PhD · PRINCIPAL_INVESTIGATOR · Wake Forest University Health Sciences
Who to contact
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Inclusion
Exclusion
What this trial measures
- Depressive Symptom ScoresBaseline
Improvement in depressive symptoms, indication by either remission (PHQ-9 score \<5) or a 50% reduction in PHQ-9 score. The Patient Health Questionnaire (PHQ-9) is a self-report tool that incorporates DSM-IV depression diagnostic criteria with other leading major depressive symptoms. The too rates the frequency of the symptoms which factors into the scoring severity index. PHQ-9 scores of 5, 10, 15, and 20 represent mild, moderate, moderately severe and severe depression.
- Depressive Symptom ScoresMonth 3
Improvement in depressive symptoms, indication by either remission (PHQ-9 score \<5) or a 50% reduction in PHQ-9 score. The Patient Health Questionnaire (PHQ-9) is a self-report tool that incorporates DSM-IV depression diagnostic criteria with other leading major depressive symptoms. The too rates the frequency of the symptoms which factors into the scoring severity index. PHQ-9 scores of 5, 10, 15, and 20 represent mild, moderate, moderately severe and severe depression.
- Depressive Symptom ScoresMonth 6
Improvement in depressive symptoms, indication by either remission (PHQ-9 score \<5) or a 50% reduction in PHQ-9 score. The Patient Health Questionnaire (PHQ-9) is a self-report tool that incorporates DSM-IV depression diagnostic criteria with other leading major depressive symptoms. The too rates the frequency of the symptoms which factors into the scoring severity index. PHQ-9 scores of 5, 10, 15, and 20 represent mild, moderate, moderately severe and severe depression.
- Depressive Symptom ScoresMonth 9
Improvement in depressive symptoms, indication by either remission (PHQ-9 score \<5) or a 50% reduction in PHQ-9 score. The Patient Health Questionnaire (PHQ-9) is a self-report tool that incorporates DSM-IV depression diagnostic criteria with other leading major depressive symptoms. The too rates the frequency of the symptoms which factors into the scoring severity index. PHQ-9 scores of 5, 10, 15, and 20 represent mild, moderate, moderately severe and severe depression.
- Depressive Symptom ScoresYear 1
Improvement in depressive symptoms, indication by either remission (PHQ-9 score \<5) or a 50% reduction in PHQ-9 score. The Patient Health Questionnaire (PHQ-9) is a self-report tool that incorporates DSM-IV depression diagnostic criteria with other leading major depressive symptoms. The too rates the frequency of the symptoms which factors into the scoring severity index. PHQ-9 scores of 5, 10, 15, and 20 represent mild, moderate, moderately severe and severe depression.