Dallas 2K: A Natural History Study of Depression
{ "Dallas 2K: Understanding Depression Over Time", "This study, called Dallas 2K, is looking at how depression changes over 10 years in 2,500 people. It's an observational study, meaning you won't receive any new treatments or medications as part of the study. Researchers will gather information about your lifestyle, health, and biology to understand what helps or hinders recovery from depression. They are particularly interested in how severe your depression symptoms are over time, measured by a questionnaire called the PHQ-9. You can join if you are 10 years old or older, can speak and understand English, and have symptoms of a depressive disorder.", "design": "This is an observational study involving 2,500 participants. It is a natural history, longitudinal, prospective study, meaning researchers will follow participants over time.", "commitments": "You will have clinician-rated and participant-rated assessments, and provide blood, saliva, stool, and urine samples. You may also have EEG (brain wave measurement) and MRI (imaging) scans, and an optional m-health study via phone app or wristband, all over 10 years.", "compensation": "Not stated in the trial record.", "follow_up": "Your depression severity will be measured over 10 years.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Dallas 2K: A Natural History Study of Depression
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Madhukar Trivedi, MD · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Longitudinal changes in depression severity of subjects with elevated symptomatology on Patient Health Questionnaire (PHQ-9) for non-psychotic depressive disorders.10 years
Assessment of changes in depressive symptom severity over time using PHQ- total scores in participants with non-psychotic depressive disorders.