Cerebellar Stimulation and Cognitive Control Study

This study is exploring if a treatment called Repetitive Transcranial Magnetic Stimulation (rTMS) can help improve thinking and mood in people with certain conditions. rTMS uses magnetic pulses to stimulate a part of the brain called the cerebellum. Researchers want to see if stimulating the cerebellum can help restore normal brain activity in people with schizophrenia, autism spectrum disorder, bipolar disorder, depression, and Parkinson's disease. You might be able to join if you are between 18 and 90 years old and have one of these diagnoses. The study will measure success by looking at changes in symptom rating scales specific to each condition, like the MADRS for bipolar disorder or PANSS for schizophrenia. The current status of this study is unclear, but it plans to enroll 200 participants.

Study design
This is an interventional study that plans to enroll 200 participants. Some participants will receive active rTMS, while others will receive sham (inactive) rTMS.
What's involved
You would have 5 to 6 separate visits for treatment, with rTMS or sham stimulation twice daily for 5 days. There will also be 3 follow-up visits, including cognitive, disease-specific, emotional, EEG, and MRI testing.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 1 week, 3 weeks, and 2 months after the stimulation treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03217110

Cerebellar Stimulation and Cognitive Control

Recruiting
NAAges 18–90InterventionalBasic science
Krystal Parker, PhD
~200 participants
Updated 2026-03-19 on ClinicalTrials.gov
What's tested:Repetitive Transcranial Magnetic Stimulation (rTMS)Sham Repetitive Transcranial Magnetic Stimulation (rTMS)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in disease-specific symptom rating scale, one scale identified for each group (MADRS for bipolar group; PANSS for schizophrenia group; UPDRS in Parkinson's patient group).
Measured over During the 1 week of treatment, with follow up 1 week, 3 weeks, and 2 months post-stimulation.
Schizophrenia
Autism Spectrum Disorder
Bipolar Disorder
Depression
Parkinson Disease

NCT03217110

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Iowa

    Iowa City, Iowastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Krystal L Parker, Ph.D · PRINCIPAL_INVESTIGATOR · Univeristy of Iowa

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Eligibility criteria

Inclusion

A clinical diagnosis consistent with enrollment

Exclusion

History of recurrent seizures or epilepsy
Any other neurological or psychiatric diagnosis outside the diagnosis for which the participant is enrolled.
Active substance use disorder in the past 6 months other than tobacco use disorder.
Inability to consent for study.
Pacemaker
Coronary Stent
Defibrillator
Neurostimulation
Claustrophobia
Uncontrolled high blood pressure
Atrial fibrillation
Significant heart disease
Hemodynamic instability
Kidney disease
Pregnant, trying to become pregnant, or breast feeding
  • Change in disease-specific symptom rating scale, one scale identified for each group (MADRS for bipolar group; PANSS for schizophrenia group; UPDRS in Parkinson's patient group).During the 1 week of treatment, with follow up 1 week, 3 weeks, and 2 months post-stimulation.

    Change between pre- and post-assessments.