Cerebellar Stimulation and Cognitive Control Study
This study is exploring if a treatment called Repetitive Transcranial Magnetic Stimulation (rTMS) can help improve thinking and mood in people with certain conditions. rTMS uses magnetic pulses to stimulate a part of the brain called the cerebellum. Researchers want to see if stimulating the cerebellum can help restore normal brain activity in people with schizophrenia, autism spectrum disorder, bipolar disorder, depression, and Parkinson's disease. You might be able to join if you are between 18 and 90 years old and have one of these diagnoses. The study will measure success by looking at changes in symptom rating scales specific to each condition, like the MADRS for bipolar disorder or PANSS for schizophrenia. The current status of this study is unclear, but it plans to enroll 200 participants.
- Study design
- This is an interventional study that plans to enroll 200 participants. Some participants will receive active rTMS, while others will receive sham (inactive) rTMS.
- What's involved
- You would have 5 to 6 separate visits for treatment, with rTMS or sham stimulation twice daily for 5 days. There will also be 3 follow-up visits, including cognitive, disease-specific, emotional, EEG, and MRI testing.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 1 week, 3 weeks, and 2 months after the stimulation treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Cerebellar Stimulation and Cognitive Control
At a glance
Conditions
NCT03217110
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Iowa
Iowa City, Iowastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Krystal L Parker, Ph.D · PRINCIPAL_INVESTIGATOR · Univeristy of Iowa
Who to contact
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Inclusion
Exclusion
What this trial measures
- Change in disease-specific symptom rating scale, one scale identified for each group (MADRS for bipolar group; PANSS for schizophrenia group; UPDRS in Parkinson's patient group).During the 1 week of treatment, with follow up 1 week, 3 weeks, and 2 months post-stimulation.
Change between pre- and post-assessments.