rTMS for Depression After Spinal Cord Injury
This study is looking into a new way to treat depression in people who have had a spinal cord injury (SCI). It will test a treatment called repetitive transcranial magnetic stimulation (rTMS), which is a non-invasive brain stimulation. The study aims to see if rTMS is safe and how well it helps reduce symptoms of depression. You might be able to join if you are between 18 and 70 years old, had an SCI at least six months ago, and have major depressive disorder. The study will involve 14 participants. Success will be measured by tracking any side effects and how much depressive symptoms improve over five weeks.
- Study design
- This is an interventional study involving 14 participants. The specific phase of the study is not mentioned.
- What's involved
- Participants will receive rTMS treatment five days a week for four weeks. Depressive symptoms will be assessed at the beginning, at week 3, and at week 5.
- Compensation
- Not stated in the trial record.
- Follow-up
- Safety will be assessed throughout the 5-week study period, and depressive symptoms will be measured at 5 weeks after treatment begins.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Treatment of Depression Post-SCI
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Catherine VanDerwerker, DPT, PhD · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina
Who to contact
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What this trial measures
- Safety as assessed by number of adverse eventsThrough the study period (5 weeks)
Report of adverse and serious adverse events in all participants.
- Number of visits missedThroughout the treatment period (4 weeks)
The average of the number of intervention visits missed across all participants
- Change in depressive symptoms as assessed by the Hamilton Rating Scale for DepressionBaseline, midpoint (Week 3), and post treatment (5 weeks)
The Hamilton Rating Scale for Depression consists of 17 questions with a total score range from 0 - 52. Ranges of total score include the following: 0 - 7 suggests normal/no depressive symptoms; 8 - 16 suggests mild depressive symptoms; 17 - 23 suggests moderate depressive symptoms; and 24 - 52 suggests severe depressive symptoms.