Studying Brain Activity in Pain and Depression

This study is looking at how the brain works in people with chronic pain or depression, and in healthy individuals. We want to see if certain patterns of brain activity, called "transdiagnostic biomarkers," can help us better understand and group different types of thinking problems. You would play computer games/tasks like N-back, COGED, PacMan, Bandit, and Websurf, and complete online health surveys about pain, sleep, depression, anxiety, and PTSD. The main goal is to see if these methods are practical and can be used to find these brain activity patterns. We are looking for 45 participants in total, including those with pain or depression, and healthy volunteers. The study is currently unclear on its recruitment status.

Study design
This is an interventional study involving 45 participants, divided into three groups: healthy controls, individuals with chronic pain, and individuals with depression.
What's involved
You would participate in computer games/tasks and complete online health surveys. The feasibility of all study aspects will be measured within 1-7 days.
Compensation
Not stated in the trial record.
Follow-up
The study's feasibility is measured within 1-7 days, which suggests a short follow-up period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04864080

Transdiagnostic Cognitive Biomarkers

Recruiting
NAAges 18+InterventionalDiagnostic
University of Minnesota
~45 participants
Updated 2026-03-04 on ClinicalTrials.gov
What's tested:Computer game/taskHealth surveys online

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility for all aspects of the study
Measured over 1-7 days
Pain
Depression
1 sites across 1 states
Minnesota1

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Have access to the online study platform.
Pain or depression

Exclusion

under 18, non-English speaking
pregnant women
  • Feasibility for all aspects of the study1-7 days

    Feasibility; the overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depression as well as healthy controls.