Protein, Mobility Therapy, and Electric Stimulation for Older ICU Survivors
This study is looking at how a combination of treatments can help older adults who have been in the intensive care unit (ICU) and are now experiencing muscle weakness (sarcopenia) and critical illness. The treatments include mobility-based physical rehabilitation (MRP), high protein supplements (HPRO), and neuromuscular electric stimulation (NMES). Researchers want to see if these treatments can improve muscle mass and strength, and reduce inflammation. You may be eligible if you are 60 to 99 years old, had a long ICU stay, can follow commands in English, and were mobile before your ICU stay. The study aims to enroll 78 participants.
- Study design
- This interventional study plans to enroll 78 participants aged 60-99 years old. The specific phase of the study is not mentioned.
- What's involved
- Participants will receive mobility-based physical rehabilitation five times a week, high whey protein shakes, and neuromuscular electric stimulation. Muscle mass, strength, and systemic inflammation will be measured at various times over 28 days.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for changes in muscle mass, muscle strength, and systemic inflammation for up to 28 days.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Change in Muscle massDays 0 to 14 to 28
Muscle mass will be measured by lower extremity muscle CT scans to calculate muscle volume and cross sectional area.
- Change in Muscle strengthDays 0, 7, 14, 21 and 28
Handgrip strength obtained using a hand grip dynamometer and manual muscle testing using hand held dynamometer
- Change in Systemic InflammationDays 0, 7, 14, 21 and 28
Quantitative analysis of CRP, IFN-γ, IL-1α, IL-1β, IL-6, and IL-8.