Protein, Mobility Therapy, and Electric Stimulation for Older ICU Survivors

This study is looking at how a combination of treatments can help older adults who have been in the intensive care unit (ICU) and are now experiencing muscle weakness (sarcopenia) and critical illness. The treatments include mobility-based physical rehabilitation (MRP), high protein supplements (HPRO), and neuromuscular electric stimulation (NMES). Researchers want to see if these treatments can improve muscle mass and strength, and reduce inflammation. You may be eligible if you are 60 to 99 years old, had a long ICU stay, can follow commands in English, and were mobile before your ICU stay. The study aims to enroll 78 participants.

Study design
This interventional study plans to enroll 78 participants aged 60-99 years old. The specific phase of the study is not mentioned.
What's involved
Participants will receive mobility-based physical rehabilitation five times a week, high whey protein shakes, and neuromuscular electric stimulation. Muscle mass, strength, and systemic inflammation will be measured at various times over 28 days.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for changes in muscle mass, muscle strength, and systemic inflammation for up to 28 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05326633

Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors

Not Yet Recruiting
EARLY_PHASE1Ages 60–99InterventionalTreatment
University of Maryland, Baltimore
~78 participants
Updated 2026-05-06 on ClinicalTrials.gov
What's tested:MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Muscle mass
Measured over Days 0 to 14 to 28
+2 more outcomes measured
Critical Illness
Sarcopenia
ICU Acquired Weakness
1 sites across 1 states
Maryland1

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  • Change in Muscle massDays 0 to 14 to 28

    Muscle mass will be measured by lower extremity muscle CT scans to calculate muscle volume and cross sectional area.

  • Change in Muscle strengthDays 0, 7, 14, 21 and 28

    Handgrip strength obtained using a hand grip dynamometer and manual muscle testing using hand held dynamometer

  • Change in Systemic InflammationDays 0, 7, 14, 21 and 28

    Quantitative analysis of CRP, IFN-γ, IL-1α, IL-1β, IL-6, and IL-8.