Critical Illness clinical trials
53 active trials name this condition. Describe your situation to see which ones you may be eligible for.
By location
- iNO300 Therapy in Critically Ill Patients With Pneumonia
- Music Listening: A Mechanistic Trial
- Exogenous Ketone Supplementation in ICU Delirium
- Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention
- Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle
- A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
- Behavioral Economic & Staffing Strategies in the ICU
- Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients
- Goal-Directed Sedation in Mechanically Ventilated Infants and Children
- Preoperative Fasting vs. Not Fasting in Critically Ill Patients
- Optimizing Recovery in Trauma Patients by Integrating Enhanced Nutrition Delivery
- PICU-related Sleep and Circadian Dysregulation Pilot Study
- MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients
- Bright Light Exposure in Surgical Patients
- RCT: Early Feeding After PEG Placement
- End-Tidal Oxygen for Intubation in the Emergency Department
- Digital and Plasma Biomarkers in Delirium
- Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients
- The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial (Cardiac Output Study)
- Exhaled Breath: A Novel Technique for Rapid Diagnosis of Respiratory Diseases and Infections
- Evaluating the Unmet Needs of Older Adults to Promote Functional Recovery After a Critical Illness
- NIBP Validation Study
- Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
- Establishing Normative Data for Pupillometer Assessments in Neuro-Intensive Care
- Critical Health Assessment and Outcomes Score/Study
- SC2i Tissue and Data Repository Protocol
- Muscle Recovery After Critical Illness
- Pathological Myeloid Activation After Sepsis and Trauma
- Pervasive Sensing and AI in Intelligent ICU
- The Family Perspectives Project Pilot Trial
- Embedded Palliative Care in the MICU
- PUSH-IT Continuing Enteral Feeds for Tracheostomy
- Improving Needs Among Older Adults
- VoiceLove: An App-Based COMMunication Tool Designed to Address DeliriUm and Improve Family ENgagement and PatIent/Family SatisfaCtion in CriticAlly Ill PaTiEnts (COMMUNICATE)
- Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
- The Effects of Endotracheal Suctioning on Pain and Serum Markers
- Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
- COMPARE-VENT Feasibility Pilot Study
- Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial
- Fluorescent Probe for Assessment of Renal Elimination
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children
- Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress: the Lift RCT
- REFRAME: an Emotion Regulation Intervention to Improve Psychological Outcomes in Surrogate Decision-Makers of the Critically Ill
- Examination of Personalized SpO2 Targets
- Gastric Ultrasound in Tube Fed Intubated Patients
- Enhancing Parent/Caregiver Engagement in the Pediatric Intensive Care Unit (PICU): A PICU Journal
- Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial
- Tube Size Randomized Trial During Emergency Tracheal Intubation
- UW ISeqU: Clinical Impact of Whole-genome Sequencing in Adults
- Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes
Guides for people searching for a trial
- Why people get turned down — and what to do nextWhat eligibility criteria are for, what keeps people out, and where to go when the first door closes.
- How your biomarkers decide which trials you qualify forEGFR, HER2, BRAF, PD-L1 and the rest — what they are and why they increasingly gate access.
- How to search for a trial without losing your mindWhere to look, what to gather first, and how to read what you find.
- What Phase 1, 2 and 3 actually mean for youWhat each phase is testing, and how to weigh an early-phase trial against a later one.
- 10 questions to ask before you say yesTreatment, time, cost, safety and your rights. Worth bringing to a screening visit.
- You matched with a trial. What happens now?Phone screens, the screening visit, informed consent, and day one.
Showing active trials that list “Critical Illness” as a condition. Eligibility shown on each trial is an estimate — the trial's study team makes the final decision.