NCT07643467

Fluorescent Probe for Assessment of Renal Elimination

Not Yet Recruiting
PHASE4Ages 18–65InterventionalDiagnostic
Aaron Cook
~200 participants
Updated 2026-06-16 on ClinicalTrials.gov
What's tested:RelmapirazinIohexolMedibeacon tGFR monitorUrine creatinine clearance collection

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Transdermal Glomerular Filtration Rate (tGFR) Monitoring Accuracy
Measured over 8 Hours
Augmented Renal Clearance
Critical Illness
1 sites across 1 states
Kentucky1
  • Aaron M Cook, PharmD · PRINCIPAL_INVESTIGATOR · University of Kentucky College of Pharmacy, Department of Pharmacy Practice & Science
  • Juan-Carlos Aycinena, MD · STUDY_DIRECTOR · University of Kentucky College of Medicine, Department of Nephrology

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Eligibility criteria

Inclusion

18-65 years old
critically ill or acutely ill hospitalized patients admitted to the intensive care unit
Stable/normal renal function

Exclusion

Prisoners
Pregnant women
Laboratory evidence of unstable kidney function (KDIGO AKI stage 1-3--This includes subjects with Scr \> 1.5x baseline)
  • Transdermal Glomerular Filtration Rate (tGFR) Monitoring Accuracy8 Hours

    Accuracy of transdermal glomerular filtration rate (GFR) monitoring compared with measured urine creatinine clearance.