Study of a Sleep Chronobundle for Critically Ill Patients
This study is looking at a new approach called a "sleep chronobundle" to help critically ill patients in the Medical Intensive Care Unit (MICU) improve their sleep and body clock alignment. The chronobundle includes bright daytime light, timed meals, extra mobility sessions, and efforts to promote sleep overnight by rescheduling non-urgent care and dimming lights. The study aims to see if this bundle can help align your body's natural rhythms and improve sleep and metabolism. You might be able to join if you are an adult MICU patient needing breathing support or medication to maintain blood pressure. The study hopes to enroll 160 patients, but its current status is unclear.
- Study design
- This is an interventional study planning to enroll 160 participants. It will test a "sleep chronobundle" intervention.
- What's involved
- Participants will receive bright daytime light, timed meals, extra mobility sessions, and overnight sleep promotion. These interventions will start on day 1 and continue throughout your MICU stay.
- Compensation
- Not stated in the trial record.
- Follow-up
- The main goal of the study is measured 72 hours after the treatment ends.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle
At a glance
Conditions
Where it's being run
2 sites across 1 statesStudy leadership
- Melissa P Knauert, MD, PhD · PRINCIPAL_INVESTIGATOR · Yale University
Who to contact
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What this trial measures
- Circadian alignment based on diurnal heart rate variationpost-treatment, 72 hours
Individual heart rate nadir compared to population normal nadir of 04:00. Maximum difference +/- 12 hours.