COMPARE-VENT Feasibility Pilot Study for Respiratory Failure in Cardiac Patients
This study is looking at different ways to use mechanical ventilation (a machine that helps you breathe) in patients who have heart disease and also need help breathing. Specifically, it's comparing two types of ventilation: Volume Controlled Mode and Pressure Controlled Mode. The goal is to see how well these methods can be used in a cardiac intensive care unit (CICU) and how quickly patients can start on their assigned ventilation mode. You might be able to join if you are an adult (18 or older) admitted to the cardiac ICU, need invasive mechanical ventilation for more than 12 hours, and have conditions like respiratory failure or cardiogenic pulmonary edema (fluid in the lungs due to heart problems). This study aims to improve how we care for patients with heart and breathing issues.
- Study design
- This is an interventional pilot study planning to enroll 75 participants. It will compare two different modes of mechanical ventilation.
- What's involved
- Participants will be monitored from enrollment until 48 hours after starting their assigned mechanical ventilation mode.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for adherence to the assigned study mode and time to initiation of the assigned mode, both measured from enrollment to 48 hours.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
COMPARE-VENT Feasibility Pilot Study
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Adherance to assigned study mode (Feasibility Outcome)Enrollment to 48 hours
Percentage of time spent on the assigned study mode while receiving invasive mechanical ventilation in the cardiac ICU between enrollment and 48 hours after enrollment.
- Time From Enrollment to Initiation of Assigned Mode of Mechanical Ventilation (Feasibility Outcome)Enrollment to 48 Hours
Time (number of hours) taken to initiate participants from enrollment (cardiac ICU admission) to initiation of assigned study mode of invasive mechanical ventilation upto 48 hours after enrollment.