Understanding Pain and Stress During Endotracheal Suctioning in ICU Patients
This study is looking at how endotracheal tube (ETT) suctioning, a routine procedure for patients on breathing machines (ventilators) in the Intensive Care Unit (ICU), affects pain and stress in the body. We want to see if this procedure, which helps keep airways clear, increases pain levels, measured by a tool called CPOT (Critical-Care Pain Observation Tool). We also want to find out if it raises certain chemicals in the blood, like hypoxanthine, that can show stress and a lack of oxygen. You might be able to join if you are an adult (18 or older) in the ICU with conditions like flu, pneumonia, COVID, or sepsis, are on a ventilator, have an arterial line, and need ETT suctioning. The study aims to enroll 110 participants. The status of this study is currently unclear.
- Study design
- This is an interventional study aiming to enroll 110 adult participants. It is designed to observe the effects of a standard medical procedure.
- What's involved
- You would undergo endotracheal tube suctioning as part of your normal care. Blood samples would be taken at baseline and 30 minutes after suctioning to measure certain chemicals.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pain level and blood markers will be measured at baseline and 30 minutes after suctioning.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Effects of Endotracheal Suctioning on Pain and Serum Markers
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Elizabeth Johnston Taylor, PhD, FAAN · PRINCIPAL_INVESTIGATOR · Loma Linda University School of Nursing
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Impact of ETT suctioning on subject pain levelChange between baseline CPOT score and 30-minutes post suctioning CPOT score.
The Critical-Care Pain Observation Tool (CPOT) is a composite measurement used to assess pain in non-verbal ICU patients by evaluating four behavioral indicators: facial expression, body movements, muscle tension, and ventilator compliance (for intubated patients) or vocalization (for non-intubated patients). Each indicator is scored from 0 (no pain behavior) to 2 (intense pain behavior), resulting in a total score from 0 to 8. Higher scores indicate higher pain levels, guiding clinicians in pain management. For example, a score of 0 indicates no pain, while a score of 2 in any category suggests more severe pain, prompting possible adjustments in analgesic care.
- Impact of ETT suctioning on subject serum markers of hypoxia and oxidative stress (Hypoxanthine).Change between baseline serum marker blood draw and 30-minutes post suctioning serum marker blood draw
Serum markers will be obtained via arterial line blood draw 5 minutes pre-ETT suctioning and again post-ETT suctioning. Normal blood concentrations of hypoxanthine in healthy adult individuals are less than 5 µmol. Levels greater than 5 µmol indicate hypoxia and oxidative stress.