Digital CBT for Insomnia and Depression in U.S. Military Veterans

This study is exploring digital versions of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Cognitive Behavioral Therapy for Depression (CBT-D) for U.S. Military Veterans who experience both insomnia and depression. You might be eligible if you are an English-speaking U.S. Military Veteran with specific scores for depression and insomnia. The study aims to see if treating insomnia and depression in a specific order works better than treating just one condition, and to find out which digital treatments are best for different individuals. Success will be measured by whether both your depression and insomnia symptoms improve significantly after 3 months. The study plans to enroll 1200 participants, but its current status is unclear.

Study design
This is a large randomized study with 1160 participants. It compares five different approaches: digital CBT-I alone, digital CBT-D alone, digital CBT-I followed by CBT-D, digital CBT-D followed by CBT-I, and a mood monitoring group.
What's involved
You would access digital interventions through a mobile-optimized web app and have access to an intervention coach/guide as needed. The study measures outcomes at 3 months post-treatment.
Compensation
Not stated in the trial record.
Follow-up
Your progress will be checked 3 months after treatment to see if your depression and insomnia have improved.

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NCT05456607

Digital CBT for Insomnia and Depression

Recruiting
NAAges 18+InterventionalTreatment
University of Rochester
~1,200 participants
Updated 2026-07-15 on ClinicalTrials.gov
What's tested:Cognitive Behavioral Therapy for InsomniaCognitive Behavioral Therapy for DepressionMood Monitoring

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Dual Remission of Depression and Insomnia
Measured over 3 Months post-treatment
Depression
Insomnia
1 sites across 1 states
New York1
  • Wilfred Pigeon, PhD · PRINCIPAL_INVESTIGATOR · University of Rochester

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

English-speaking
U.S. Military Veterans
endorse depression (Patient Health Questionnaire-depression score \> 10)
endorse insomnia (Insomnia Severity Index score \> 10).

Exclusion

pregnancy
history of bipolar disorder
history of psychosis
current use of anti-psychotic medications or mood stabilizers (e.g., lithium)
current suicidal ideation with active intent
  • Dual Remission of Depression and Insomnia3 Months post-treatment

    The proportion of participants achieving dual remission in each study arm with Depression Remission defined as a total score of \< 5 on the Patient Health Questionnaire (PHQ-9) and Insomnia Remission defined as a total score of \< 8 on the Insomnia Severity Index (ISI).