Back to search results

Understanding Engagement with Digital Mental Health for Depression and Anxiety

This study is looking for people aged 18-75 who are Mass General Brigham primary care patients and have symptoms of depression (PHQ-9 score of 10 or higher) and/or anxiety (GAD-7 score of 8 or higher). You also need to own a smartphone and be fluent in English. The study aims to understand what helps people use a mobile app called IntelliCare Plus, which uses techniques from cognitive-behavioral therapy to help with depression and anxiety. Researchers will test two strategies to improve engagement: automated motivational messages and support from a coach. Success will be measured by how many minutes you use the app and your weekly self-reports on your symptoms. The study is currently recruiting 76 participants.

Study design
This is an interventional study with 76 planned participants. You would be randomly assigned to receive different engagement strategies alongside the IntelliCare Plus app.
What's involved
You would use the IntelliCare Plus app for an 8-week period. The study will also involve weekly self-reports of your clinical outcomes.
Compensation
Not stated in the trial record.
Follow-up
Your intervention use will be measured over an 8-week period. Short-term engagement will be measured for 3 hours after each decision point during this 8-week period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05555875

Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II

Completed
NAAges 18+InterventionalHealth services
Brigham and Women's Hospital
~76 participants
Updated 2026-09-02 on ClinicalTrials.gov
What's tested:SilverCloud

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Time to disengagement
Measured over 8-week intervention period
+1 more outcome measured

Conditions

Depression
Anxiety Disorders

Explore related trials

Anxiety DisorderDepression

NCT05555875

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Jessica Morrow Lipschitz

    Boston, Massachusettsno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Jessica M Lipschitz, PhD · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Mass General Brigham primary care patient
Age 18+
Clinically significant symptoms of depression (Patient Health Questionnaire-9 (PHQ-9) greater than or equal to 10) and/or anxiety (Generalized Anxiety Disorder-7 (GAD-7) greater than or equal to 8)
Owns a smartphone capable of running the study applications
Fluent in English.

Exclusion

Diagnosis of bipolar I or bipolar II disorder per patient report or the patient's medical record
Diagnosis of any psychotic disorder per patient report or the patient's medical record
Current substance use disorder per patient report or the patient's medical record
Acute and/or unstable medical problem that may interfere with participation (e.g., scheduled for surgery in the next two months).

What this trial measures

  • Time to disengagement8-week intervention period

    disengagement from the digital mental health intervention is defined as the first week of \<1 minute of use after which there are no subsequent weeks with at least 1 minute of use

  • Intervention Engagement Within 3 Hours Following a Decision Point - Proximal (Short-Term)For 3 hours after each decision point, over the 8-week intervention period

    Intervention use logs will be collected continuously and automatically throughout the intervention period on the system backend. Proximal Intervention engagement will be operationalized as whether or not the intervention was used within 3 hours of a decision point (i.e., the point at which participants in the automated motivational messaging arms were randomized to receive or not receive an automated motivational message). This outcome only applies to participants randomized to receive automated motivational messaging.