Precision Medicine for Emotion Regulation

This study is testing different ways to help people manage their emotions better. You might learn skills like "Checking the Facts" (looking at evidence for your thoughts), "Opposite to Emotion Action" (doing the opposite of what your emotions tell you), or "Mindfulness of Current Emotions" (observing your feelings without judgment). The goal is to see if personalized training in these skills works better than standard training to reduce daily negative emotions. We are looking for 390 participants who are at least 18 years old and have difficulty regulating their emotions. Success will be measured by changes in your positive and negative feelings over 42 days. The study's status is currently unclear.

Study design
This interventional study plans to enroll 390 participants. It aims to first test personalized versus standardized emotion regulation skills, then assign participants to optimal or non-optimal skills based on initial findings.
What's involved
You will be asked to report on your positive and negative feelings 7 times per day for 42 days.
Compensation
Not stated in the trial record.
Follow-up
Your positive and negative feelings will be measured for 42 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05651295

A Precision Medicine Approach to Target Engagement for Emotion Regulation

Recruiting
NAAges 18+InterventionalTreatment
Matthew Southward, PhD
~390 participants
Updated 2026-05-11 on ClinicalTrials.gov
What's tested:Checking the FactsOpposite to Emotion ActionMindfulness of Current Emotions

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Changes in Positive and Negative Affect Schedule-Short Form
Measured over 7 times per day for 42 days
Emotional Regulation
Depression
Anxiety
Borderline Personality Disorder
Obsessive-Compulsive Disorder
Posttraumatic Stress Disorder
Eating Disorders
1 sites across 1 states
Ohio1
  • Matthew W Southward, Ph.D. · PRINCIPAL_INVESTIGATOR · Ohio State University

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Elevated emotion dysregulation

Exclusion

Lack of proficiency in English
No access to smartphone
Conditions requiring greater than outpatient care
  • Changes in Positive and Negative Affect Schedule-Short Form7 times per day for 42 days

    A self-report measure designed to assess the intensity of momentary negative affect. Scores range from 1 to 5, with higher scores indicating greater negative affect and lower scores indicating less negative affect.