This is an observational study looking at Gaucher disease. Researchers want to understand how problems with lysosomes (small parts of cells that break down waste) might affect tiny particles called extracellular vesicles (EVs). They are studying the quantity and size of these EVs in people with Gaucher disease, carriers of the Gaucher gene, and healthy individuals. The goal is to see if changes in EVs could help identify new ways to understand and track Gaucher disease, especially since EVs can cross into the brain. They will measure EV quantity at the start and after 3 months, and EV size at the start. You can join if you are between 18 and 80 years old, have a confirmed Gaucher diagnosis, are a confirmed carrier, or are a healthy control without the GBA1 gene mutation. The study is currently recruiting about 30 participants.

Study design

This is an observational study with no intervention, meaning participants will not receive any new treatments. It plans to enroll about 30 participants.

What's involved

EV quantity will be measured at baseline and again at 3 months. EV size will be measured at baseline.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for at least 3 months, based on the endpoint measurements.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.