Back to search results

SilverCloud for Depression and Anxiety in Youth

This study is testing a program called SilverCloud, which is an app-based Cognitive Behavioral Therapy (CBT) program, to see how well it works for high school students with depression and anxiety. It's also looking at how easy it is to use in schools. You could be eligible if you are between 13 and 22 years old, enrolled in high school, and have a score of 10 or higher on a depression (PHQ-9) or anxiety (GAD-7) questionnaire. The study will measure changes in your depression and anxiety scores at the beginning and after 8 weeks. This study is currently recruiting 120 participants.

Study design
This is an interventional study with a planned enrollment of 120 participants. It is an open trial, meaning both participants and researchers will know which treatment is being received.
What's involved
The primary endpoints for this study are measured at baseline and Week 8. This suggests participation will involve assessments at these two time points.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints are measured at Baseline and Week 8, indicating a follow-up period of at least 8 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06004414

SilverCloud as a School-Based Intervention for Vulnerable Youth

Recruiting
NAAges 13–22InterventionalHealth services
NYU Langone Health
~120 participants
Updated 2026-03-30 on ClinicalTrials.gov
What's tested:App-based Cognitive Behavioral Therapy (CBT)Psychotherapy

At a glance

Recruiting sites
1 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Patient Health Questionnaire-9 (PHQ-9) Score
Measured over Baseline, Week 8
+1 more outcome measured

Conditions

Depression
Anxiety

Explore related trials

AnxietyDepression

NCT06004414

Where you'd take part

This study runs at 3 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Northwell Health School Mental Health Partnership sites

    Glen Oaks, New Yorkno site contact published

    Not yet recruiting

  • NYU Langone Health

    Brooklyn, New Yorkno site contact published

    Recruiting

  • Rutgers University

    New Brunswick, New Jerseyno site contact published

    Not yet recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Anna Van Meter, PhD · PRINCIPAL_INVESTIGATOR · NYU Langone Health
  • Erum Nadeem, PhD · PRINCIPAL_INVESTIGATOR · Rutgers University

Who to contact

Anna Van Meter, PhD
[email protected]
646-754-5085
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Enrolled in a high school
Score of 10+ on GAD-7 or PHQ-9
Speak/read English. The current investigational version of SilverCloud that will be used in this study is only available in English.
Enrolled in 9th through 11th grades.
Score of 10+ on GAD-7 or PHQ-9
Enrolled in one of the study sites
Speak/read English. The current investigational version of SilverCloud that will be used in this study is only available in English.

Exclusion

Does not use a smartphone
Mental health concerns for which intensive treatment is indicated. Because SilverCloud has not been evaluated in people with serious mental illness, participants who exhibit symptoms of mania or psychosis will be referred to a higher level of care.
Current suicidal ideation with intent. Participants who have a suicide plan and intent to act on it will be referred to the SBHC suicide risk protocol and will not be eligible until their suicidal thoughts have abated.
Current (within 1 month of enrollment) mental health treatment at one of the study sites
Does not use a smartphone
Mental health concerns for which intensive treatment is indicated. Because SilverCloud has not been evaluated in people with serious mental illness, participants who exhibit symptoms of mania or psychosis will be referred to a higher level of care.
Current suicidal ideation with intent. Participants who have a suicide plan and intent to act on it will be referred for crisis intervention through the site at which they were referred and will not be eligible until their suicidal thoughts have abated.

What this trial measures

  • Change in Patient Health Questionnaire-9 (PHQ-9) ScoreBaseline, Week 8

    The PHQ-9 is a 9-item questionnaire assessing the degree of depression severity. Items are ranked on a 4-point scale ranging from 0 (not at all) to 3 (nearly every day). The total score is the sum of responses and ranges from 0-27; higher scores indicate greater severity of depression.

  • Change in General Anxiety Disorder-7 (GAD-7) ScoreBaseline, Week 8

    The GAD-7 is a 7-item questionnaire assessing the degree of anxiety severity. Items are ranked on a 4-point scale ranging from 0 (not at all) to 3 (nearly every day). The total score is the sum of responses and ranges from 0-21; higher scores indicate greater severity of anxiety.