Adolescent Mood During Puberty and Testosterone

This study is exploring how puberty and hormones might affect mood in adolescents, specifically looking at why depression rates change differently for girls and boys during this time. It's testing a 4-week mobile program called "Healthy Minds Program" which aims to improve coping and emotion regulation skills. You might be able to join if you are between 11 and 14 years old, have your own mobile device, and have experienced a stressful life event recently or have moderate depression (a CES-DC score of 16 or higher). The study will measure changes in your depression symptoms (CES-DC Score) over up to 8 weeks to see if the program is helpful. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 60 participants. It is not specified if it is randomized or blinded.
What's involved
You would participate in a 4-week mobile program and have your depression symptoms measured for up to 8 weeks.
Compensation
Not stated in the trial record.
Follow-up
Your depression symptoms will be measured for up to 8 weeks after starting the program.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06072677

Adolescent Mood During Puberty and Testosterone

Recruiting
NAAges 11–14Interventional
University of North Carolina, Chapel Hill
~60 participants
Updated 2026-01-14 on ClinicalTrials.gov
What's tested:Healthy Minds Program

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
CES-DC Score Over Time
Measured over up to Week 8
Adolescent Depression

NCT06072677

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Carolina Crossing B, Suite 1

    Chapel Hill, North Carolinastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Elizabeth Andersen, PhD · PRINCIPAL_INVESTIGATOR · University of North Carolina, Chapel Hill

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Eligibility criteria

Inclusion

Between the ages of 11 and 14
Have their own personal mobile device and capability to download the MyCap and Healthy Minds apps
Experienced a stressful life event within the last year, or endorse moderate depression (defined by a CES-DC score 16 or higher)

Exclusion

Previous experience with the Healthy Minds Program
Regular meditation practice
Current or history of manic episodes, psychotic symptoms, or current suicidal intent
Taking any form of exogenous hormones or intrauterine device (IUD) within one month of participation in the study
Taking medications that directly alter cardiovascular or neurological function
  • CES-DC Score Over Timeup to Week 8

    The 20-item Center for Epidemiological Studies Depression Scale for Children (CES-DC) will be the primary measure of severity of depressive symptoms. Each item is rated 0 (not at all) to 3 (a lot), with items 4, 8, 12, and 16 being reversed scored. The total CES-DC score may range from 0-60. Higher scores indicate more severe depressive symptoms. Scores of 15 or greater are suggestive of significant depressive symptoms. The overall CES-DC score will be assessed at the end of each week in the study.