Improving Total Knee Replacement Satisfaction with a Personalized Approach

This study is testing if a personalized approach can improve satisfaction after total knee replacement surgery (TKA). You might be eligible if you are between 18 and 80 years old, speak English, and are scheduled for a first-time, single knee replacement. The study will compare standard care to a personalized approach that includes a "TKA Personalized Outcome Prediction Tool" to help set expectations, along with targeted support for mental health and physical therapy before surgery. The main goal is to see if this personalized approach leads to more patients feeling satisfied with their knee replacement one year after surgery. The current recruitment status is unclear.

Study design
This is a randomized controlled trial, meaning participants will be randomly assigned to either the standard care group or the personalized approach group. The study plans to enroll 300 participants.
What's involved
You would complete questionnaires using MyChart before surgery. If eligible and you consent, an enrollment visit will occur 2-3 months before your surgery to discuss the study.
Compensation
Not stated in the trial record.
Follow-up
The study will measure your satisfaction one year after your surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06298721

Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

Recruiting
NAAges 18–80InterventionalTreatment
The Cleveland Clinic
~300 participants
Updated 2026-06-11 on ClinicalTrials.gov
What's tested:Personalized outcome prediction tool + targeted interventionsStandard of Care TKA

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Satisfaction at 1 year
Measured over 1 year
Knee Osteoarthritis
Knee Arthropathy
Surgery

NCT06298721

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Cleveland Clinic Foundation

    Cleveland, Ohiostudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Nicolas S Piuzzi, MD · PRINCIPAL_INVESTIGATOR · Cleveland Clinic Ohio

Opens a ready-to-send draft in your own email app — review before sending.

  • Satisfaction at 1 year1 year

    Patient Acceptable Symptom State (PASS) anchoring question of: "Taking into account all the activity you have during your daily life, your level of pain and also your activity limitations and participation restrictions, do you consider the current state of your knee satisfactory?" to measure satisfaction