Accelerated rTMS for Stimulant Use Disorder and Depression

This study is looking at an accelerated form of repetitive Transcranial Magnetic Stimulation (rTMS) for people with both depression and stimulant use disorder (like cocaine or methamphetamine use). rTMS is a treatment that uses magnetic fields to stimulate nerve cells in the brain. You would receive up to 50 rTMS sessions over three weeks, with each session lasting about 10 minutes and breaks in between. The main goal of this small study is to see if this accelerated rTMS treatment is practical and can be done effectively. We are looking for 40 participants aged 18-65 who use stimulants at least 10 days in the month before joining.

Study design
This is a small, open-label study, meaning both you and the study team will know what treatment you are receiving. It plans to include 40 participants.
What's involved
You would receive up to four rTMS sessions per day, five days a week, for a total of 50 sessions over three weeks. You would also have EEG (brain wave test), ECG (heart test), urine drug screens, and complete questionnaires.
Compensation
Not stated in the trial record.
Follow-up
You will have a follow-up visit one week after your last rTMS session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06424184

Accelerated rTMS for Substance Use Disorder and Depression

Recruiting
NAAges 18–65InterventionalTreatment
University of Texas Southwestern Medical Center
~40 participants
Updated 2026-08-24 on ClinicalTrials.gov
What's tested:Accelerated Repetitive Transcranial Magnetic Stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility of an accelerated course of repetitive Transcranial Magnetic Stimulation (rTMS).
Measured over 3 weeks
Stimulant Use
Depression

NCT06424184

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • UT Southwestern Medical Center

    Dallas, Texasno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Manish Jha, M.B.B.S · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center

Opens a ready-to-send draft in your own email app — review before sending.

  • Feasibility of an accelerated course of repetitive Transcranial Magnetic Stimulation (rTMS).3 weeks

    Feasibility will be measured by completion of at least 30 out of 50 sessions of rTMS.