IMPACT Study: Improving Mental Health for Cancer Survivors

This study, called IMPACT, is looking at a mobile app called "Moodivate" to help cancer survivors who are experiencing depression. Moodivate helps you track your daily activities and mood, and suggests new activities to improve your mood. You might be a good fit for this study if you are over 18, have cancer that is likely incurable, and have symptoms of depression. You also need to own a smartphone and be willing to use a mobile app. The study will compare people who use Moodivate to those who receive educational materials about mood management. The main goal is to see if Moodivate can reduce depression symptoms after 12 weeks. The study is currently unclear on its status and plans to enroll 279 participants.

Study design
This study will randomly assign participants to either use the Moodivate app or receive educational materials. About two-thirds of participants will use the app, and one-third will receive educational materials.
What's involved
You will complete electronic questionnaires weekly for 8 weeks, with a final follow-up questionnaire at 12 weeks. If assigned to the app group, you will use the Moodivate app during this time.
Compensation
Not stated in the trial record.
Follow-up
You will have a final follow-up questionnaire at 12 weeks after joining the study.

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NCT06582784

IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)

Recruiting
NAAges 18+InterventionalTreatment
Medical University of South Carolina
~279 participants
Updated 2026-05-22 on ClinicalTrials.gov
What's tested:Behavioral Activation Therapy AppTreatment as Usual

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Depression
Measured over 12 weeks
Depression
Depressive Symptoms
Cancer
1 sites across 1 states
South Carolina1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Age \> 18 years
ILLIC (as determined during manual chart review)
Elevated depressive symptoms, defined as a score of ≥ 8 on the PHQ-9
Current owner of an iOS- or Android-compatible smartphone
Willingness to utilize a mobile app for the treatment of depressed mood (response of "yes" on yes/no item)
Have a valid e-mail address that is checked regularly or have regular access to text messages (to access follow-up assessments)
English language fluency

Exclusion

Current suicidal ideation at study screening, defined as a response greater than or equal to 1 on item nine of the PHQ-9
Severe cognitive impairment that precludes completion of informed consent. For the purposes of assessing eligibility, this criterion is operationalized as:
Prior diagnosis of dementia, or Major Neurocognitive Disorder indicated either via self-report or in the EHR; or
Self-report of cognitive difficulties that impair functional independence
  • Change in Depression12 weeks

    Change in the Patient Health Questionnaire (PHQ-9) score from baseline. The PHQ-9 scoring is 1-27 where 1-4 is minimal depression, 5-9 is mild depression, 10-14 is moderate depression, 15-19 is moderately severe depression, and 20-27 is severe depression.