Quest to Analyze One Thousand Humans Meditating
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Tobias Moeller-Bertram, MD · PRINCIPAL_INVESTIGATOR · VitaMed Research LLC
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Effect of Meditation in an Advanced Retreat Setting on Heart Rate Variability in a Global Population4 years
In Phases 1, 2, and 3 of this study, heart rate data will be collected using a Garmin wrist device at the beginning of the meditation retreat and continuously for up to ten months after the retreat. Beat-to-beat interval data will be used to calculate heart rate variability. Time domain measures will include the mean of R-R intervals (mRR), standard deviation of all R-R intervals (SDRR), root mean square of successive R-R differences (RMSSD), and the percentage of R-R intervals that vary by at least 50 ms (pRR50). Frequency domain measures will include very low frequency (VLF), low frequency (LF), and high frequency (HF) measures.
- Effect of Meditation in an Advanced Retreat Setting on the Gut Microbiome and Metabolites in a Global Population.4 years
In Phases 1, 2, and 3 of this study, metagenomic analysis will be carried out on stool samples collected before and after the retreat. This analysis will assess changes in gut microbes and metabolites as a function of multiple variables, including age and sex.
- Effect of Meditation in an Advanced Retreat Setting on the Multi-omic Expression of Genes, Proteins, and Metabolites in the Blood in a Global Population4 years
In Phases 2 and 3 of this study, an integrative analysis of multi-omic assessments will be carried out in whole blood and plasma samples collected before and after the retreat. Whole blood will be analyzed for gene expression while proteomic and metabolomic analysis will be carried out in blood plasma.
- Effect of Meditation in an Advanced Retreat Setting on Physical and Emotional Health outcomes in a global population.4 years
In Phases 1, 2, and 3 of this study, physical and emotional states will be assessed using the Short Form (SF)-36 self-report survey instrument. This scale includes measures for the following domains: bodily pain, general health, mental health, physical functioning, role emotional, role physical, social functioning, and vitality. Data will be reported as the average percent change from baseline to follow-up for each domain. When necessary, data will be rescaled such that positive values will indicate improvement from pre- to post-retreat.