Knee Replacement Surgery: Comparing Mechanical vs. Kinematic Alignment
This study is comparing two ways to perform total knee replacement surgery (Total Knee Arthroplasty or TKA) using the Medacta SpheriKA system. One method is Mechanical Alignment (MA), the traditional approach where the new joint is placed in a neutral position. The other is Kinematic Alignment (KA), which aims to put the new joint in a position that more closely matches your knee's natural alignment. Researchers want to see if one method leads to better outcomes. You might be able to join if you are between 21 and 79 years old, need a primary TKA with the Medacta SpheriKA system, and can understand the study information. The main goal is to measure your knee function and pain using a score called KOOS-JR 6 weeks after surgery. The study is currently unclear on its recruitment status.
- Study design
- This interventional study plans to enroll 95 participants. It compares two different surgical procedures for total knee replacement.
- What's involved
- You would undergo a primary total knee replacement surgery. You would also need to be willing to return for follow-up visits.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your knee function and pain will be measured at 6 weeks after your surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty
At a glance
Conditions
NCT06617871
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Northwestern Medicine
Chicago, Illinoisstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Adam Edelstein, MD · PRINCIPAL_INVESTIGATOR · Assistant Professor of Orthopaedic Surgery
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- 6-week Knee Injury and Osteoarthritis - Joint Replacement Score (KOOS-JR)6 weeks postoperative
The Knee Injury and Osteoarthritis Score - Joint Replacement (KOOS-JR) score; range: 0 (worst knee health) - 100 (perfect knee health)