Evaluating Pain Control in Postpartum Patients on Opioid Use Disorder Medications

This study is looking at different ways to manage pain after a C-section for women who are also taking medication for opioid use disorder (SUD). Researchers want to see if one pain control method works better than others. The study will compare three approaches: a Transverse Abdominal Plane (TAP) Block with Exparel (a long-acting pain medication), Hydromorphone Patient Controlled Analgesia (PCA) given through an epidural, and an Epidural local anesthetic infusion. The main goal is to see how pain assessment scores change after surgery. You may be able to join if you are a woman between 18 and 35 years old with SUD. The study plans to enroll 20 participants, but its current status is unclear.

Study design
This is an interventional study comparing three different pain control methods. It plans to enroll 20 participants.
What's involved
Participants will receive one of three pain control methods after a C-section. Pain levels will be measured immediately after the intervention and up to two days after surgery.
Compensation
Not stated in the trial record.
Follow-up
Pain assessment scores will be measured up to post-operative day 2.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06617949

Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.

Recruiting
EARLY_PHASE1Ages 18–40InterventionalTreatment
Medical College of Wisconsin
~20 participants
Updated 2025-10-23 on ClinicalTrials.gov
What's tested:Regional AnesthesiaHydromorphone Patient Controlled AnalgelsicEpidural local anesthetic infusion

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants with Change in pain assessment scores from baseline post surgery
Measured over immediately after the study intervention and up to post op day 2
Substance Use Disorder (SUD)
2 sites across 1 states
Wisconsin2

Opens a ready-to-send draft in your own email app — review before sending.

  • Number of participants with Change in pain assessment scores from baseline post surgeryimmediately after the study intervention and up to post op day 2

    Number of participants with significant change in pain assessment scores and any association with reduction of symptoms of anxiety, depression, and overall well-being.