Substance use disorder clinical trials
131 active trials name this condition. Describe your situation to see which ones you may be eligible for.
By location
- Shared Decision Making to Treat Or Prevent (STOP) HIV in Criminal Legal Involved Populations (R33)
- Feasibility of an Interdisciplinary Intervention to Improve Care Transitions for Hospitalized Patients With Substance Use Disorders
- A Type I Hybrid Effectiveness-Implementation Trial of MIO
- Peer-Delivered Behavioral Activation in a CCBHC
- Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs)
- Project REACH: A Comprehensive Telehealth Intervention at Syringe Service Programs to Engage People Who Use Drugs
- Massed Prolonged Exposure for PTSD in Substance Use Treatment
- Utilizing Battlefield Acupuncture to Treat Chronic Pain
- A Digital Intervention to Decrease Self-Stigma Among Pregnant and Postpartum Women With Substance Use Disorder
- HIV, Equity, and Addiction Training (HEAT) Program
- Project COMET: Massed Prolonged Exposure for PTSD and SUD
- Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders
- Successful Transitions and Reintegration Tools for Veterans (START-VETS)
- Family Support Protocol for Adolescent Internalizing Disorders
- Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention
- Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain
- Cultural Adaptation of Drug Treatment for DJJ Youth
- Enhancing Addiction Treatment Through Psychoeducation
- Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth
- Written Exposure Therapy for Veterans With SUD and PTSD
- Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems
- Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.
- Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders
- Personalized Approach to Healthy Use and Recovery (PATH) Trial
- Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
- Safe & Sound Protocol in Adults With Trauma and SUD
- Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement
- Auricular Acupuncture on Emotional Distress in Service Members and Veterans With PTSD
- OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit
- CARS: Cannabis and Alcohol Reduction Study
- Substance Misuse and Family Violence Treatment Fathers
- Adolescent Stress and Substance Intervention Subsequent to Trauma
- A Randomized Controlled Trial of Digital CBT to Treat Addiction: Digital RITch®CBT vs. Standard CBT
- Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons
- Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
- Culturally Engaged REcovery: MOms Connected Through Native CommunitY
- STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking
- Pre-exposure Prophylaxis (PrEP) Adherence Intervention for Women with Substance Use Disorders
- Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs
- Preconception Intervention for Incarcerated Women With Substance Use
- An Evaluation of the Pink Cloud Application in Post- Treatment Substance Use Disorder Support
- Prevent Language Delays and Disorders Among Children of Caregivers With Substance Use Disorders With Community Groups and Individualized Services
- OurRelationship-S: A Digital Relationship-Strengthening Program for Couples Experiencing Substance Misuse
- Family Spirit Strengths
- Families Left Behind
- California MEPS Hub
- Multidimensional Sleep Health Intervention for Couples
- Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START
- SMART-r: Substance Monitoring and Active Relapse Tracking Repository
- Interprofessional Simulation Program for Clinical Resilience and Empathy: Project INSPIRE
Guides for people searching for a trial
- Why people get turned down — and what to do nextWhat eligibility criteria are for, what keeps people out, and where to go when the first door closes.
- How your biomarkers decide which trials you qualify forEGFR, HER2, BRAF, PD-L1 and the rest — what they are and why they increasingly gate access.
- How to search for a trial without losing your mindWhere to look, what to gather first, and how to read what you find.
- What Phase 1, 2 and 3 actually mean for youWhat each phase is testing, and how to weigh an early-phase trial against a later one.
- 10 questions to ask before you say yesTreatment, time, cost, safety and your rights. Worth bringing to a screening visit.
- You matched with a trial. What happens now?Phone screens, the screening visit, informed consent, and day one.
Showing active trials that list “Substance use disorder” as a condition. Eligibility shown on each trial is an estimate — the trial's study team makes the final decision.