This study, called Project COMET, is looking at a treatment called Massed Prolonged Exposure Therapy (M-PE) for adults who have both Posttraumatic Stress Disorder (PTSD) and Substance Use Disorders (SUD). M-PE is a type of therapy delivered over a shorter time frame, like 10 sessions in 2-4 weeks, compared to weekly sessions. Researchers want to see if M-PE can better reduce PTSD symptoms and substance use compared to standard SUD care. They will also look at other important outcomes like depression, suicidal thoughts, and quality of life. You may be able to join if you are 18 or older, are already in SUD treatment, and meet criteria for both PTSD and SUD. The study is currently unclear on its recruitment status and plans to enroll 168 participants.

Study design

This is an interventional study comparing Massed Prolonged Exposure Therapy (M-PE) to standard outpatient SUD care. It plans to enroll 168 participants.

What's involved

Participants will receive either Massed Prolonged Exposure Therapy (M-PE) over 2-4 weeks or standard intensive outpatient SUD treatment, which includes resilience groups, peer support, and individual therapy.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for 6 months after randomization, with assessments at 6 weeks, 10 weeks, 18 weeks, and 30 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.